Grants and contracts awarded to Yale School of Medicine

March/April 2005


  • George Aghajanian, NIH, Psychotogenic Drug Action on Chemically Defined Neurons, 4 years, $931,200
  • Thomas Biederer, NIH, Mechanisms of Syncam-Induced Synapse Formation, 5 years, $1,445,391
  • Jonathan Bogan, NIH, Proteomic Characterization of Insulin Signaling Targets, 2 years, $327,000
  • Richard Bungiro, NIH, Mucosal Immune Responses in Hookworm Infection, 2 years, $163,500
  • Edward Chu, NIH, Molecular Regulation of Translational Regulation, 4 years, $886,720
  • Lauren Cohn, NIH, T Cell Control of Airway Mucus Production, 5 years, $2,043,750
  • Ralph DiLeone, NIH, Investigating the Role of Leptin Signaling in the Ventral Tegmental Area, 2 years, $400,125
  • Gail D’Onofrio, NIH, Enhancing Emergency Room Physician-Performed Alcohol Interventions in the Emergency Department, 5 years, $3,461,863
  • Durland Fish, Department of Agriculture, Eco-Epidemiology of Emerging Arthropod-Borne Pathogens in the Northeast, 1 year, $300,781
  • Gerald Friedland, NIH, New England Program for AIDS Clinical Trial—PROACT, 1 year, $802,492
  • Guadalupe Garcia-Tsao, NIH, Cirrhosis and Its Complications, 5 years, $775,659
  • Peter Glazer, NIH, Cisplatin Damage Response and Cell-to-Cell Communication, 5 years, $1,446,633
  • Ruth Halaban, NIH, Epigenetic Chromatin Changes as Melanoma Markers, 2 years, $281,220
  • Hatim Hassan, NIH, Mechanisms of Regulation of Anion Exchanger SLC26A6, 5 years, $710,100
  • Michael E. Hodsdon, NIH, Structural Basis of Prolactin Receptor Recognition, 5 years, $1,465,139
  • Mark Horowitz, NIH, Regulation of Bone Remodeling by Megakaryocytes, 5 years, $1,798,500
  • Themis Kyriakides, NIH, MCP-1 and Attenuation of the Foreign Body Response, 5 years, $1,524,640
  • Linda Mayes, NIH, Neurocognitive Development in Children Living in Poverty, 5 years, $2,529,478
  • David McCormick, NIH, Neurotransmitter Actions in Neocortex and Thalamus, 4 years, $1,660,477
  • Laura Ment, NIH, Multicenter Randomized Indomethacin Intraventricular Hemorrhage Prevention Trial, 5 years, $6,965,242
  • Pramod Mistry, NIH, Patient-Oriented Research in Inherited Metabolic Liver Diseases, 5 years, $738,291
  • Michael Nathanson, NIH, Ca2+ Waves in Hepatocytes: Mechanisms and Effects, 5 years, $486,127
  • Paul Noble, NIH, Regulation of Pulmonary Fibrosis by CXCR3, 4 years, $1,635,000
  • Lynne Regan, NIH, High-Throughput Assays for Inhibitors of Protein-Protein Interactions, 3 years, $975,058
  • Jennifer Ruger, NIH, Economic Evaluation of Addiction Services, 3 years, $445,818
  • Raymond Russell, NIH, Function and Regulation of Cardiac Uncoupling Proteins, 4 years, $1,308,000
  • Joseph Santos-Sacchi, NIH, Membrane Properties of Cells Comprising the Outer Hair Cell System, 5 years, $2,388,206
  • Gerald Shadel, Department of the Army, Nuclear-Mitochondrial Signals That Control Oxidative Stress Resistance and Longevity, 3 years, $294,034
  • Albert Shaw, NIH, Top3 Homologues in Lymphocyte Genome Stability and Aging, 5 years, $355,175
  • Dieter Soll, NIH, Studies on Transfer RNA, 4 years, $5,345,449
  • Stefan Somlo, NIH, Genetics of Autosomal Dominant Polycystic Liver Disease, 5 years, $2,401,172
  • Carlos Stocco, NIH, Regulation of Estradiol Production by Prostaglandin F2alpha, 2 years, $163,500
  • Stephen Strittmatter, NIH, Molecular Determinants of Axonal Regeneration, 4 years, $1,512,376
  • Peter Takizawa, NIH, Mechanism of mRNA Transport by Myo4p, 5 years, $1,379,288
  • Sandra Wolin, NIH, RNA Quality Control and Environmental Stress, 4 years, $1,316,769
  • Lawrence Young, NIH, Regulation of Glucose Transport in the Ischemic Heart, 4 years, $1,471,500

  • Richard Bucala, Alliance for Lupus Research, Macrophage Migration Inhibitory Factor Inhibition in Systemic Lupus Erythematosus, 1 year, $250,000
  • Ronald Duman, Organon Inc., Influence of Organon #2448 and Organon #26576 on Neurogenesis in the Adult Hippocampus, 1 year, $221,160
  • Marie Egan, Cystic Fibrosis Foundation, The Effects of Curcumin Treatment on the Function of Delta F508 Cystic Fibrosis Transmembrane Conductance Regulator, 1 year, $108,000
  • Alan Garen, Sidney Kimmel Cancer Center, Targeting Vessels in Tumors, 5 years, $168,067
  • Susan Kaech, Edward Mallinckrodt Jr. Foundation, Identifying the Genes That Regulate Formation of Memory CD8 T Cell Precursors, 3 years, $50,000
  • Elias Lolis, Robert Leet and Clara Guthrie Patterson Trust, Identification of the Allosteric Sites of CXCR4, 1 year, $75,000
  • Stephen Malawista, G. Harold and Leila Y. Mathers Charitable Foundation, Leukocytes and Inflammation, 1 year, $110,000
  • David Morris, Robert Leet and Clara Guthrie Patterson Trust, Pathogenesis of Fibrotic Lung Disease, 1 year, $75,000
  • David Rimm, Breast Cancer Alliance Inc., Spectral-Spatial Imaging to Detect Premalignancy in Breast Tissue Samples, 1 year, $100,000
  • Craig Roy, Health Research Inc., Coxiella burnetii Type IV Effector Proteins, 1 year, $163,500
  • Gerald Shadel, Robert Leet and Clara Guthrie Patterson Trust, Genetic Transformation of Mitochondria: Toward Mouse Models and Human Gene Therapy for Mitochondrial Diseases and Aging, 1 year, $75,000
  • Stefan Somlo, Mizutani Foundation for Glycoscience, The Role of N-Glycosylation in Human Polycystic Diseases, 1 year, $46,442
  • Zhaoxia Sun, Edward Mallinckrodt Jr. Foundation, Chemical Suppression of Polycystic Kidney Disease in Zebrafish, 1 year, $50,000
  • Flora Vaccarino, Tourette Syndrome Association Inc., Inhibitory Interneurons in the Cerebral Cortex of Patients with Tourette’s Syndrome, 1 year, $74,558
  • Li Wen, Juvenile Diabetes Research Foundation International, Tolerance Induction by Insulin Reactive and TGFß Producing T Cells, 3 years, $165,000
  • Kevin White, Columbia University, Integrated Approaches to Hox-Regulated DNA Elements, 1 year, $131,415
  • Graham Williams, Astra Zeneca, L.P., Characterization of the Neurobiological Consequences of Acute Alpha-7 Treatment in the Nonhuman Primate: Identification of the Potential for Improving Cognitive Function in Schizophrenia, 1 year, $230,875