Grants and contracts awarded to Yale School of Medicine

July/August 2005


  • Serap Aksoy, NIH, Trypanosome Gene Expression in Tsetse, 2 years, $163,500
  • Robert Alpern, NIH, Regulation of Renal Bicarbonate and Chloride Absorption, 5 years, $2,043,750
  • Roland Baron, NIH, Role of the c-SRS Proto-Oncogene in Osteoblasts, 5 years, $1,798,500
  • Sumita Bhaduri-McIntosh, NIH, Early Cellular Immune Responses to EBV, 4 years, $535,680
  • Angelique Bordey, NIH, GABA Signaling in the Postnatal Subventricular Zone, 4 years, $1,483,007
  • Robert Camp, NIH, Qualitative Analysis of Tissue Biomarkers and Pathways, 2 years, $281,220
  • Michael Caplan, NIH, Ion Pump Partners: Regulators of Sorting and Function, 4 years, $1,702,179
  • Sonia Caprio, NIH, Pathophysiology of Type 2 Diabetes in Youth, 5 years, $2,043,750
  • R. Todd Constable, NIH, Epileptogenic Tissue Localization Using EEG-fMRI, 4 years, $1,500,511
  • Joseph Craft, NIH, Immune Responses in Lupus, 5 years, $1,635,000
  • Ralph DiLeone, NIH, Role of the Orexin Neuropeptide in Responses to Morphine, 5 years, $1,455,000
  • Daniel DiMaio, NIH, Cell Transformation by Bovine Papillomavirus, 5 years, $2,630,896
  • Ronald Duman, NIH, Antidepressants and Signal Transduction and Gene Expression, 5 years, $1,818,750
  • Jack Elias, NIH, Protease/Cathepsin-Mediated Apoptosis in COPD, 4 years, $1,635,000
  • Jorge Galan, NIH, Molecular Genetic Analysis of Salmonella Cell Invasion, 1 year, $2,343,717
  • Joel Gelernter, NIH, Genetics of Opioid Dependence, 5 years, $5,779,192
  • Sankar Ghosh, NIH, Subversion of Innate Immune Responses by Brucella, 2 years, $433,750
  • Thomas Gill, NIH, Epidemiology of Disability and Recovery in Older Persons, 5 years, $3,152,866
  • Daniel Goldstein, NIH, Strategies to Enhance Immunity in Aging, 3 years, $648,000
  • Carlos Grilo, NIH, Patient-Oriented Research with a Focus on Eating and Weight Disorders, 5 years, $597,160
  • Steven Hebert, NIH, Structure and Function of ROMK Channel in Kidney, 4 years, $1,370,692
  • Zeev Kain, NIH, Parent/Health Care Provider Behaviors & Child’s Anxiety, 5 years, $2,659,446
  • Harlan Krumholz, NIH, Telemonitoring to Improve Heart Failure Outcomes, 4 years, $6,664,663
  • Nian Liu, NIH, Content-Based Indexing and Retrieval of Brain Odor Maps, 3 years, $470,339
  • Angeliki Louvi, NIH, Development of Choroid Plexus and the Blood-CSF Barrier, 2 years, $395,933
  • Shrikant Mane, NIH, Yale Microarray Center for Research on the Nervous System, 5 years, $6,509,106
  • Linda Mayes, NIH, Cortical Maturation and ERPS in Cocaine-Exposed Children, 5 years, $631,800
  • Diane McMahon-Pratt, NIH, Intervenable Host Leishmania (Viannia) Interactions, 5 years, $5,166,089
  • Thomas Morgan, NIH, Genetic Risk Factors for Myocardial Infarction, 5 years, $846,072
  • A. David Paltiel, NIH, Evaluating the Link Between HIV Prevention and Treatment, 3 years, $1,487,112
  • Jordan Pober, NIH, Human CTL-Mediated Injury of Graft Endothelial Cells, 5 years, $2,177,410
  • Marc Potenza, NIH, fMRI of Craving in Addictions: Gender Differences, 5 years, $1,604,920
  • Kenneth Pugh, NIH, Neurobiological Foundations in Reading (Dis)Ability, 5 years, $2,970,826
  • Timothy Quan, NIH, The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus, 5 years, $613,967
  • Gary Rudnick, NIH, Structure and Function of NSS Transporters, 4 years, $1,238,981
  • Charles Sanislow, NIH, Cognitive Control in Borderline & Trauma Psychopathology, 5 years, $887,895
  • William Sessa, NIH, Regulation of Vascular Remodeling & Angiogenesis by Nogo, 5 years, $2,043,750
  • Nenad Sestan, NIH, Molecular Control of Cortical Neural Stem Cells, 5 years, $1,717,912; NIH, Neurobiology of Speech and Language Development, 4 years, $1,512,376
  • Albert Shaw, NIH, Top3 Homologues in Lymphocyte Genome Stability and Aging, 5 years, $1,417,925
  • Dieter Söll, NSF, Expanding the Genetic Code with Phosphoserine and Pyrrolysine, 1 year, $171,569
  • Stephen Strittmatter, NIH, Axonal Growth Cone Signal Transduction, 4 years, $1,512,376
  • Zhaoxia Sun, NIH, SCO, a Zebrafish Model, Links Cilia and Kidney Cysts, 5 years, $1,921,125
  • Patrick Sung, NIH, DNA Repair Genes & Proteins of the RAD52 Group, 5 years, $1,941,565
  • Edwin Thrower, NIH, Pancreatic Zymogen Activation in a Reconstituted System, 2 years, $260,800
  • Helen Treloar, NIH, Development of the Primary Olfactory Pathway, 5 years, $1,430,625
  • Marietta Vazquez, NIH, Epidemiology of Human Metapneumovirus Infection, 5 years, $676,986
  • Marney White, NIH, Craving, Binge Eating, and Obesity, 5 years, $671,571
  • John Wysolmerski, NIH, Function of the Calcium-Sensing Receptor in the Breast, 5 years, $1,675,875

  • Patrick Allen, National Alliance for Research on Schizophrenia and Depression, Analysis of Protein Phosphatase-Mediated Glutamate Receptor Regulation, 2 years, $60,000
  • George Anderson, University of Pittsburgh, Neurobiology, Impulsivity and Alcoholism, 4 years, $45,404
  • Titus Boggon, American Society of Hematology, Structure/Function Studies of Janus Kinase Family Members, 1 year, $50,000
  • Alfred Bothwell, Robert Leet and Clara Guthrie Patterson Trust, Bioengineering Functional Islets for Treatment of Type 1 Diabetes, 1 year, $59,999
  • H. Kim Bottomly, Mount Sinai School of Medicine, Immunobiology of Peanut Allergy and Its Treatment: A Prototype, 5 years, $239,654
  • Demetrios Braddock, American Cancer Society, Inc., Molecular Determinants of Nucleic Acid Recognition by KH Domains, 2 years, $720,000
  • Christopher Breuer, American Surgical Association, Investigating the Growth Potential of Tissue-Engineered Venous Conduits in a Juvenile Lamb Model, 2 years, $75,000
  • Darlene Brunzell, National Alliance for Research on Schizophrenia and Depression, Beta2 Nicotinic Acetylcholine Receptors Affect Schizophrenia Phenotypes via Modulation of CREB, 2 years, $59,968
  • João Cabral, American Heart Association (Heritage Affiliate), Biophysical Studies of a Bacterial Cyclic Nucleotide-Regulated Channel, 3 years, $198,000
  • Cecilia Canessa, American Heart Association (Heritage Affiliate), Functional Analysis of SGK1 in Vivo, 3 years, $198,000
  • Daniel Chase, National Parkinson Foundation, Inc., Identification of the Molecular Mechanisms of Dopamine Signaling, 1 year, $40,000
  • Yung-Chi Cheng, Kagoshima University, Novel Nucleoside Reverse Transcriptase Inhibitors Active Against Multi-Drug Resistance HIC-1, 1 year, $35,736
  • Hongbo Chi, Arthritis National Research Foundation, SIPI-Mediated Regulation of Autoimmune Disease, 1 year, $50,000
  • Chuhan Chung, American Liver Foundation, Hepatocellular Carcinoma and Hepatic Stellate Cells Express Antiangiogenic Pigment Epithelium-Derived Factor; Epigenetic Regulation of PEDF Occurs Through DDR2 Activation on HSC, 3 years, $225,000
  • David Cone, National Academies of Emergency Dispatch, Can EMD Conserve ScarceEMSResources?, 1 year, $3,500
  • Vladimir Coric, National Alliance for Research on Schizophrenia and Depression, Endocannabinoid Receptor Modulation and Obsessive-Compulsive Disorder: A Double Blind, Placebo-Controlled Pilot Study of Dronabinol Addition in Serotonin-Reuptake Inhibitor-Resistant OCD, 2 years, $59,760
  • Kristina Crothers, American Lung Association, Chronic Obstructive Pulmonary Disease in HIV-Positive Compared to HIV-Negative Patients, 1 year, $40,000
  • Madison Cuffy, The Thoracic Surgery Foundation for Research and Education, The Role of Indoleamine 2,3-Diosygenase (IDO) on Modulation of Immune Responses in Inflammatory Arterial Diseases, 2 years, $50,000
  • Jan Czyzyk, American Cancer Society, Inc., Alternative Effectors of Ras GTPase in T Cell Activation, 4 years, $720,000
  • Pietro De Camilli, G. Harold and Leila Y. Mathers Charitable Foundation, Molecular Mechanisms of Synaptic Vesicle Biogenesis, 3 years, $1,650,179
  • Marie Egan, Cystic Fibrosis Foundation, Cystic Fibrosis Center, 1 year, $55,310
  • Barbara Ehrlich, American Society of Nephrology, Regulation and Function of Polycystin-2, 1 year, $50,000
  • Richard Flavell, Bill and Melinda Gates Foundation, A Mouse Model to Evaluate Live Attenuated Vaccine Candidates, 5 years, $16,968,506; Alzheimer’s Association, An Inducible Mouse to Elucidate the Role of Immunity/Inflammation in AD, 3 years, $234,498
  • Gerald Friedland, Virginia Commonwealth University, Opioids and HIV Medications: Interactions in Drug Users, 1 year, $37,632
  • Mark Gerstein, Rutgers University, Structural Genomics of Eukaryotic Domain Families, 5 years, $230,041
  • Daniel Goldstein, American Society of Transplantation, Role of the Innate Immune Ligand Heat Shock Protein 70 in Transplantation, 2 years, $80,000
  • Jonathan Grauer, Medtronic, Inc., New Zealand White Rabbit Pseudarthrosis Study Evaluating INFUSE and CRM Products, 1 year, $210,138
  • Handan Gunduz-Bruce, National Alliance for Research on Schizophrenia and Depression, GABA-Glutamate Interactions and Psychosis, 2 years, $30,000
  • Ann Haberman, The S.L.E. Foundation, Inc., How Germinal Centers Select High-Affinity B Cells: Determination of Cellular Interactions and Migratory Behavior via Intravital Microscopy, 3 years, $150,000
  • Ala Haddadin, Union Mutual Foundation, High-Dose Statin Therapy in the Preoperative Period, 2 years, $25,000
  • Bryan Hains, Pfizer, Inc., Pifzer Scholars in Pain Medicine, 2 years, $123,000
  • Martha Harding, AGA Foundation for Digestive Health and Nutrition, Hepatitis C Virus Infection of Human Liver-Chimeric Mice, 3 years, $195,000
  • Lise Heginbotham, American Heart Association (Heritage Affiliate), Regulation of Ca2+ Transport Proteins, 3 years, $198,000
  • Josephine Hoh, The Ellison Medical Foundation, Trans-Racial Gene Mapping for Age-Related Macular Degeneration, 4 years, $200,000
  • Akiko Iwasaki, Burroughs Wellcome Fund, Stromal Cell Contributions in Innate and Adaptive Immune Response to Mucosal Viral Infection, 5 years, $400,000
  • Jeffrey Kahn, American Heart Association (Heritage Affiliate), The Role of a Novel Human Coronavirus in Kawasaki Disease, 3 years, $198,000
  • Insoo Kang, American Foundation for AIDS Research, The Effect of Aging on IL-7 Mediated CD8+ T Cell Survival, 2 years, $60,000
  • Anil Karihaloo, National Kidney Foundation, VEGF Signaling in Renal Tubular Epithelia, 1 year, $100,000
  • Stuart Katz, American Heart Association, Erythropoietin in Acute Myocardial Infarction, 1 year, $66,000
  • Barbara Kazmierczak, L2 Diagnostics, LLC, Virulence Typing of Pseudomonas Clinical Isolates, 1 year, $158,204
  • Judith Kidd, University of Florida, Taste Psychophysics, 1 year, $76,779
  • Fadi Lakkis, American Society of Nephrology, Model Organism to Study Innate Allorecognition, 1 year, $50,000
  • Angelika Lampert, Epilepsy Foundation of America, Control of Excitability in Rodent Spike-Wave Seizures by Voltage-Gated Sodium Channels, 1 year, $40,000
  • Brian Leaderer, Brigham and Women’s Hospital, Gene by Environment Interactions in Asthma and Allergy, 1 year, $185,331
  • Patty Lee, American Lung Association, MIMED Mechanisms of VEGF and HO-1, 1 year, $60,000
  • Xin Li, Arthritis Foundation, Role of Borrellia burgdoferi NapA in Lyme Arthritis, 2 years, $150,000
  • Yi-Hwa Liu, American Heart Association (Heritage Affiliate), Development of Quantitative High Resolution and High Sensitivity for Targeted Molecular Imaging, 3 years, $198,000
  • Elias Lolis, The Campbell Foundation, CXCR4 Allosteric Agonists, 1 year, $11,603
  • Gero Miesenböck, The Dana Foundation, Illuminating the Function of Hypothalamic Feeding Circuits, 3 years, $300,000
  • Angus Nairn, Rockefeller University, Molecular Actions of Neuroleptic Drugs, 1 year, $288,288
  • Michael Nitabach, Whitehall Foundation, Inc., Clock-Membrane Coupling in Circadian Pacemaker Neurons, 1 year, $75,000
  • Aldo Peixoto, Satellite Research, Hemodynamic and Hormonal Response to Dialysate Sodium Individualization in Hemodialysis Patients, 1 year, $50,000
  • Patricia Preisig, University of Texas Southwestern Medical Center at Dallas, The Formulation of a Rational Therapy of Nephrolithiasis, 3 years, $123,703
  • Timothy Quan, Arthritis Foundation, The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus, 2 years, $150,000; Abbott Laboratories, Inc., The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus, 1 year, $72,000
  • Gary Rudnick, National Alliance for Autism Research, Mutation Associated with Asperger’s Syndrome—Effect on Amine Transporter System, 2 years, $120,275
  • Raymond Russell, Dr. Robert C. Atkins Foundation, Effects of a High-Protein Ketogenic Diet on Myocardial Metabolism, 1 year, $91,615
  • Kristi Sacco, National Alliance for Research on Schizophrenia and Depression, Effects of Atomoxetine on Cognitive Function in Schizophrenia, 2 years, $60,000
  • Mary Schwab-Stone, Fundación Quiera, Quiera-Yale Children of the Street, 1 year, $10,211
  • Gerald Shadel, A-T Childrens’ Project, Aberrant Regulation of Mitochondrial DNA in Ataxia-Telangiectasia, 2 years, $42,263
  • Arthur Simen, National Alliance for Research on Schizophrenia and Depression, Quantitative Trait Mapping in a Large Mormon Pedigree with Severe Depression and Anxiety, 2 years, $60,000
  • Albert Sinusas, GE Healthcare Ltd., Evaluation of Ventricular Remodeling in Animals Using SPECT Imaging After Myocardial Infarction, 7 months, amount confidential
  • William Sledge, Eli Lilly and Company, YNHH Recidivist Program Prevention Evaluation with Six Sigma Methodology, 1 year, $129,553
  • Stefan Somlo, The Joseph LeRoy and Ann C. Warner Fund, Inc., ARPKD Research, 1 year, $25,000
  • Julie Sosa, Patrick and Catherine Weldon Donaghue Medical Research Foundation, Neurocognitive Changes in Primary Hyperparathyroidism, 3 years, $179,374
  • Julie Staley-Gottschalk, National Alliance for Research on Schizophrenia and Depression, Antidepressant-Mediated Adaptations in Nicotinic Acetylcholine Receptor Expression, 2 years, $60,000
  • Mary Tomayko, Dermatology Foundation, Phenotypic and Functional Analysis of Memory B cells, 3 years, $165,000
  • Flora Vaccarino, National Alliance for Autism Research, Molecular Mechanisms of Cerebral Cortical Overgrowth, 2 years, $119,276
  • Lisa Walke, American Geriatrics Society, Barriers to and Facilitators of Effective Symptom Management in Older Adults with Chronic Obstructive Pulmonary Disease, 2 years, $130,000
  • Li Wen, American Diabetes Association, Inc., The Role of Toll in Autoimmune Diabetes, 3 years, $300,000
  • Kevin White, University of California–Riverside, Molecular Bases of Ecdysteroid Action in the Mosquito, 5 years, $157,982
  • Catherine Yeckel, American Diabetes Association, Inc., Mild Cold Exposure: A Non-Pharmacological Approach to Improve Insulin Sensitivity In Obese Youth, 3 years, $414,000
  • Mark Yeckel, National Parkinson Foundation, Inc., Dopaminergic and Cholinergic Control of Inhibitory Connectivity Between Direct and Indirect Output Pathways of the Neostriatum Background, 1 year, $40,000
  • Jiasheng Zhang, American Society of Nuclear Cardiology, Imaging of Matrix Metalloproteinase Activity in Thoracic Aortic Aneurysm: A Pilot Study, 1 year, $25,000