Grants and contracts awarded to Yale School of Medicine

May/June 2009


  • Philip Askenase, NIH, The Role of AIDS in Contact Sensitivity, 2 years, $455,125
  • Sonia Caprio, NIH, Metabolic Markers and Predictors of Childhood Obesity, 5 years, $1,373,650
  • Kelly Cosgrove, NIH, Dopaminergic and Endocannabinoid Interactions in Nicotine Dependence, 1 year, $194,700
  • Jared Davis, NIH, Investigating the Mechanism of mRNA Cleavage in the Ribosomal A-Site, 2 years, $96,856
  • Robin de Graaf, NIH, Cerebral Metabolic Flux Mapping using Oxygen-17 NMR, 2 years, $903,284
  • Ralph DiLeone, NIH, Development of Neuronal Tracers to Study Leptin Modulation of Dopamine Circuits, 2 years, $389,125
  • Maria Diuk-Wasser, NIH, Determining the Reservoir for Host-Targeted Control Measures to Prevent Lyme Disease, 2 years, $165,500
  • Robert Dubrow, NIH, Framework Program for Global Health at Yale University, 2 years, $270,000
  • Barbara Ehrlich, NIH, Regulation of Cholangiocytes by InsP3 Receptor Isoforms, 4 years, $1,729,897
  • Sorin Fedeles, NIH, Molecular Pathogenesis of Autosomal Dominant Polycystic Liver Disease (ADPLD), 2 years, $50,988
  • Erol Fikrig, NIH, Circadian Regulation of Innate Immune Mechanisms of Viral Recognition, 2 years, $455,125
  • Jorge Galán, NIH, Molecular Mechanisms of Salmonella typhi Pathogenicity, 2 years, $631,892
  • Alison Galvani, NIH, Impacts of Individual and Social Behavior on Influenza Dynamics and Control, 5 years, $2,986,225
  • Kevan Herold, NIH, Yale Autoimmunity Center of Excellence, 5 years, $3,886,266
  • Sohail Husain, NIH, Ryanodine Receptor in Pancreatitis, 5 years, $1,731,406
  • Melinda Irwin, NIH, Impact of Exercise on Ovarian Cancer Prognosis, 5 years, $3,375,064
  • Akiko Iwasaki, NIH, NLR Control of Antiviral Defense in the Respiratory Mucosa, 2 years, $455,125
  • Susan Kaech, NIH, Determining How Adjuvants Alter Effector and Memory T Cells during Vaccination, 2 years, $455,125; NIH, Control of Effector and Memory T Cell Development by Inflammatory Signals, 5 years, $2,060,662
  • Barbara Kazmierczak, NIH, Regulation of Motility and Organelle Assembly at the Pseudomonas aeruginosa Pole, 2 years, $820,950
  • David Kingery, NIH, Exploring the Transition State of Ribosomal Peptide Bond Catalysis, 2 years, $41,176
  • Anthony Koleske, NIH, Regulation of Invadopodia Formation in Breast Cancer Cells, 2 years, $618,142
  • Haiqun Lin, NIH, Longitudinal Study of Transitions in Disability and Death among Older Persons, 3 years, $989,825
  • James Mazer, NIH, Allocation and Control of Visual Attention, 2 years, $768,627
  • Gil Mor, NIH, Function of Toll-Like Receptors Throughout Gestation, 5 years, $5,491,503
  • Sukanya Narasimhan, NIH, Tick Midgut Proteins Critical for Borrelia Transmission, 2 years, $455,125
  • Alexander Neumeister, NIH, Serotonin 1B Receptor Imaging in Major Depressive Disorder, 2 years, $353,386
  • Michael Nitabach, NIH, Novel Analgesics from Australian Funnel-Web Spider Venom, 2 years, $455,125
  • Samuel Sathyanesan, NIH, Role of Transcription Factors in the Action of Antipsychotic Drugs, 2 years, $389,125
  • Albert Sinusas, NIH, Hybrid Volumetric SPECT/CT Imaging System, 1 year, $500,000
  • Jeffrey Sklar, NIH, Trans-Splicing of RNA in Endometrial Stroma and Other Tissues, 5 years, $1,665,114
  • Thomas Steitz, NIH, Structural Bases of the Functions of RNA-Protein Machines, 5 years, $7,732,270
  • Stephen Strittmatter, NIH, Axonal Growth Cone Signal Transduction, 3 years, $1,422,273
  • Scott Strobel, Dept. of Defense (U.S.), Investigation of Diesel Producing Fungi as a Renewable Source of Fuel, 5 years, $4,175,381
  • Joann Sweasy, NIH, DNA Polymerase Beta and Mutagenesis, 5 years, $1,628,932
  • Cenk Tek, NIH, Lifestyle Modification to Reduce Weight and Related Morbidity in Mental Illness, 2 years, $1,345,812
  • Timur Yarovinsky, NIH, Type I Interferon-Induced Protection from Staphylococcal Pore-Forming Toxins, 2 years, $443,892

  • Steven Bernstein, Montefiore Medical Center & Hospital, Trial to Test the Efficacy of a Tailored Intensive Smoking Cessation Intervention in Persons Living with AIDS, 1 year, $12,793
  • Linda Bockenstedt, Nat’l Research Fund for Tick-Borne Diseases, Inc., Real-Time Imaging of Vector-Borne Borrelia burgdorferi Infection in Mice, 1 year, $60,000
  • Mary Bogucki, Spectral Energetics, Inc., Non-Ionizing Radiation Vision for a New Army (NIRVANA), 5 months, $27,234
  • Angelique Bordey, Elsa U. Pardee Foundation, Control of Blood Flow in Glioma, 1 year, $123,963
  • Michael Cappello, March of Dimes, Mucosal Immunity to Hookworm Infection and Disease, 3 years, $300,000
  • Sreeganga Chandra, W.M. Keck Foundation, Mechanisms of Synapse Maintenance: Role in Neurodegenerative Disorders, 1 year, $25,000
  • Robert Collins, Jane Coffin Childs Memorial Fund for Medical Research, Engineering of TPR Domains to Recognize Cell-surface Receptors, 2 years, $94,583
  • Pietro De Camilli, Nat’l Alliance for Research on Schizophrenia and Depression (NARSAD), Phosphoinositide Metabolism and Psychiatric Diseases, 1 year, $99,999
  • Clare Flannery, Endocrine Fellows Foundation, Effect of Hyperinsulinemia on Endometrium, 1 year, $15,000
  • Martín García-Castro, Connecticut Innovations Inc., Molecular Profiling and Cell Fate Potential of hESC Derived Early Neural Crest Precursors, 2 years, $200,000
  • Nathan Hansen, Duke University, Brief Care-Based HIV Prevention for Newly Diagnosed Men, 1 year, $2,483
  • Kevan Herold, Duke University, Pilot, Optimization and Testing of Nanoparticulate-Based Non-Invasive Imaging in Autoimmune Disease (ACE), 1 year, $165,500; Connecticut Innovations Inc., Induction and Differentiation of Beta Cells from Human Embryonic Stem Cells, 2 years, $200,000
  • Yingqun Huang, Connecticut Innovations Inc., Molecular Function of Lin28 in Human Embryonic Stems Cells, 4 years, $500,000
  • Jeffery Kocsis, Connecticut Innovations Inc., Cellular Transplantation of Neural Progenitors Derived from Human Embryonic Stem Cells to Remyelinate the Nonhuman Primate Spinal Cord, 4 years, $500,000
  • Graciela Krikun, Aniara Diagnostica, Detection of Plasma TF Expression and Activity in Women with Endometriosis, 1 year, $5,000
  • Harlan Krumholz, National Bank of Egypt, Improving Healthcare in Egypt, 2 years, $534,492
  • Maria Lara-Tejero, Columbia University, The Interactions of Type III Secretion Effector Proteins, 10 months, $82,750
  • Qi Li, Connecticut Innovations Inc., Neural Stem Cell Responses to Hypoxia, 2 years, $200,000
  • Jun Lu, Connecticut Innovations Inc., MicroRNA Regulation of hESC Fates, 4 years, $500,000
  • Stephanie Massaro, Connecticut Innovations Inc., The Influence of Aberrant Notch Signaling on RB Mediated Cell Cycle Regulation in Acute Megakaryoblastic Leukemia, 2 years, $200,000
  • Eric Meffre, Juvenile Diabetes Research Foundation Int’l, Loss of B Cell Tolerance That is Common to RA, SLE and T1D, 7 months, $220,000
  • Angus Nairn, Michael Stern Parkinson’s Research Foundation, Identification of Neuron-Specific Protein Expression and Post-Translational Modifications Involved in Parkinson’s Disease, 1 year, $495,280
  • Kevin Pelphrey, Duke University, Longitudinal Functional Imaging of Early Childhood Anxiety Disorders, 1 year, $20,709
  • Marc Potenza, Nat’l Center for Responsible Gaming, The Yale Gambling CORE (Center of Research Excellence), 3 years, $402,498
  • Yibing Qyang, Connecticut Innovations Inc., Derivation and Functional Characterization of Heart Cells from Human Embryonic Stem Cells, 2 years, $200,000
  • Carrie Redlich, Center to Protect Workers’ Rights, Risk of Isocyanate Exposure in the Construction Industry, 1 year, $30,000
  • David Rimm, Associazione “Sandro Pitigliani” per la Lotta Contro i Tumori, Evaluation of Topoisomerase IIa Protein by a Novel Approach (AQUA, Automated Quantitative Analysis), 1 year, $27,390; SAIC-Frederick, Inc., Intrinsic Controls for Formalin-Fixed, Paraffin-Embedded Tissue, 3 years, $569,643
  • Craig Roy, Columbia University, Pathogenic Mechanisms of Coxiella burnetii, 10 months, $329,103
  • Joseph Sarhan, American Heart Association—Founders Affiliate, hnRNPs as MK2 Substrates in Leukocyte Integrin-Induced Interferon-Gamma mRNA Stabilization, 4 months, $5,000
  • Masanori Sasaki, Talecris Biotherapeutics, Inc., Combined Intravenous Immunoglobulin and Cell Therapy for Spinal Cord Injury, 2 years, $225,000
  • Nenad Sestan, March of Dimes, Molecular Control of Cortical Projection, Neuron Identity, and Connectivity, 3 years, $295,255
  • Eva Sevcsik, Max Kade Foundation, Inc., Role of Oxidative Stress in Aggregation and Membrane Interaction of Alpha-Synuclein, 1 year, $49,000
  • Steven Southwick, Mount Sinai School of Medicine, WTC RHC Data and Coordination Center, 1 year, $76,155
  • David Stern, Harry J. Lloyd Charitable Trust, Identifying New Targets for Personalizing Melanoma Therapies, 1 year, $120,000
  • Stephen Strittmatter, Wings for Life Spinal Cord Research Foundation, Imaging of Axonal Growth after Human Spinal Cord Injury, 1 year, $126,426
  • Richard Sutton, Connecticut Innovations Inc., Genome-Wide Screen to Identify hESC-Specific DNA Transcription Elements, 4 years, $500,000
  • Oyebode Taiwo, Stanford University, Disease, Disability and Death in an Aging Workforce, 1 year, $688,344
  • Hugh Taylor, John B. Pierce Laboratory Inc., Estrogen & Progesterone Effects on Orthostatic Tolerance, 2 years, $82,579
  • Penghua Wang, Northeast Biodefense Center, Roles of Auto-phagy in Flaviviral Immunity, 10 months, $82,750
  • Sandra Wolin, Connecticut Innovations Inc., Investigating the Role of Nuclear RNA Surveillance in Embryonic Stem Cells, 2 years, $200,000
  • Tian Xu, Connecticut Innovations Inc., piggyBac Transposon for Genetic Manipulation and Insertional Mutagenesis in Human Embryonic Stem Cells, 4 years, $500,000