Grants and contracts awarded to Yale School of Medicine

September/October, 2009


Federal

  • Serap Aksoy, NIH, Molecular Aspects of Tsetse and Trypanosome Transmission, 5 years, $2,326,195 *
  • Colleen Barry, NIH, Expanding Treatment for Opioid Dependence among the Privately Insured, 4 years, $1,746,305
  • Robert Beech, NIH, Progesterone-Induced Gene Expression Changes and Risk of Relapse to Cocaine Use, 2 years, $496,500 *
  • Hilary Blumberg, NIH, Biomarkers of Suicide Risk in Adolescents and Young Adults: Factors that Contribute to High Risk in Bipolar Disorder, 2 years, $998,276 *
  • Hal Blumenfeld, NIH, Preventing Spike-Wave Epileptogenesis: Critical Period and Neuroimaging Biomarkers, 2 years, $821,933 *
  • Clifford Bogue, NIH, Hex: A Homeobox Gene Essential for Liver Development, 22 months, $824,822 *
  • Martina Brueckner, NIH, Genetic Determinants of Human Heterotaxy and Aortic Arch Malformation, 6 years, $4,394,539
  • Richard Bucala, NIH, Innate and Adaptive Mechanisms in Arthritis, 5 years, $1,859,375
  • Lloyd Cantley, NIH, Cellular Repair of Kidney Injury, 21 months, $706,903 *
  • Thomas Carpenter, NIH, Classical and Non-Classical Responses to Vitamin D in Children: The Role of DBP Genotype, 2 years, $999,475 *
  • Judy Cho, NIH, Beyond Single-Point gwas: Genetics of Crohn’s Disease in Ashkenazi Jews, 22 months, $1,001,477 *
  • Hyung Chun, NIH, Role of Apelin in the Systemic and Pulmonary Vasculature, 5 years, $667,575
  • Paul Cleary, CDC/DHHS, Category 1: Meeting Community Needs Across the Prevention Spectrum, 5 years, $5,316,317
  • Joan Cook, NIH, Theory-Driven Mixed-Methods Evaluation of PTSDTreatment Implementation in VA Residential Settings, 2 years, $918,498 *
  • Lynn Cooley, NIH, Dynamic and Super-Resolution Imaging of Endogenous Proteins in Drosophila Tissues, 2 years, $946,752 *
  • Cindy Crusto, NIH, The Study of Multiple Social Determinants of Young Children’s Health, 2 years, $1,035,964 *
  • Pietro De Camilli, NIH, OCRL and the Pathogenesis of Lowe Syndrome and Dent Disease, 4 years, $1,117,760
  • Daniel DiMaio, NIH, Molecular Basis of Viral and Cellular Transformation, 5 years, $6,413,248
  • Peniel Dimberu, NIH, Role of trim Protein in Cellular Innate Anti-viral Responses to HCV, 2 years, $82,352 *
  • Claudia Dominguez, NIH, Infection and CD8 T Cell Memory: Development, Maintenance, and Plasticity, 3 years, $108,128
  • Deepak D’Souza, NIH, GABA Deficits and Vulnerability to Cannabinoid-induced Psychosis, 2 years, $374,461
  • Lynn Fiellin, NIH, Reducing Heavy Drinking to Optimize HIV/AIDSTreatment and Prevention, 5 years, $3,911,127
  • Richard Flavell, NIH, Understanding the Role of AMCase in Asthma, 2 years, $1,000,000 *
  • Ewa Folta-Stogniew, NIH, Biacore T100 SPR for Yale Keck Lab, 1 year, $363,515
  • Joel Gelernter, NIH, Genetics of Alcohol Dependence in African-Americans, 5 years, $3,193,349; NIH, Genome-wide Association Study of Cocaine Dependence in Two Populations, 2 years, $4,207,355 *
  • Sarah Gray, NIH, Mechanisms Underlying Leptin’s Attenuation of Cocaine-seeking Behavior in Rats, 2 years, $60,732 *
  • Cary Gross, Agency for Healthcare Research and Quality/DHHS,Multimorbidity and Cancer Screening: Achieving Patient Understanding, 2 years, $299,340
  • Murat Günel, NIH, Functional Genomics of the Cavenous Malformation Gene, 5 years, $2,978,125; NIH, Molecular Variants that Determine Genetic Susceptibility to Intracranial Aneurysm, 5 years, $3,265,832; NIH, Gene Discovery in Recessive Structural Brain Disorders through Whole-Exome Sequencing, 2 years, $2,906,138 *
  • David Hafler, NIH, The Role of Rare Variants in Multiple Sclerosis Risk, 2 years, $1,917,986 *
  • Kevan Herold, NIH, Type 1 Diabetes TrialNet: Clinical Center at Yale University, 5 years, $2,028,525
  • Karl Insogna, Department of Agriculture, Mechanisms of Dietary Protein-Induced Changes in Calcium Absorption Efficiency, 3 years, $499,123
  • Elizabeth Jonas, NIH, Role of Bcl-xL in Synaptic Plasticity in the Hippocampus, 2 years, $870,314 *
  • Leonard Kaczmarek, NIH, Biochemical Control of Excitability in Neurons, 2 years, $909,360 *
  • Insoo Kang, NIH, Studying the Effects of Vitamin D on FOXP3 and IL-17 Expression in Human CD4+ T Cells, 2 years, $413,750
  • Walter Kernan, NIH, Insulin Resistance Intervention after Stroke (IRIS) Trial, 5 years, $24,307,862
  • Trace Kershaw, NIH, Randomized Controlled Trial to Enhance Dual Protection among PLHIV in India, 4 years, $1,455,414
  • Ami Klin, NIH, Performance Indices of Social Disability in Toddlers with Autism, 2 years, $993,553 *
  • Michael Krauthammer, NIH, Advancing Literature Mining through Processing and Analysis, 3 years, $1,016,452
  • Suchitra Krishnan-Sarin, NIH, Incentive-Based Intervention for Smoking Cessation and Prevention in High School, 2 years, $761,988 *
  • Chiang-Shan Li, NIH, Amygdala Processes and Early Habitual Drinking, 2 years, $384,975
  • Charles Lockwood, NIH, Women’s Reproductive Health Research Career Development Program, 5 years, $2,410,115
  • Xiaomei Ma, NIH, Myelodysplastic Syndromes: Patterns of Care and Outcomes, 2 years, $417,476
  • Robert Malison, NIH, DBH, D2High and Cocaine Paranoia/Aversion: A [11C]PHNO PET Study, 2 years, $413,520 *
  • Sadie Marjani, NIH, Analyzing Allele-Specific Gene Expression and Regulation in C. albicans, 2 years, $101,764
  • Linda Mayes, NIH, ERP Neurobehavioral Assessment of Negative Reinforcement in Adolescents, 2 years, $455,125 
  • Ellena McCarthy, NIH, Cellular Dissection of Neuropeptide Signaling in the Circadian Neural Network, 3 years, $148,974
  • Justin McDonough, NIH, A Systems Biology Approach for InvestigatingCoxiella burnetii Infection, 2 years, $97,264 *
  • Sherry McKee, NIH, Dose-Ranging Study of Varenicline on Human Alcohol Self-Administration Behavior, 3 years, $1,054,468
  • David Merrick, NIH, Characterization of the Cleaved Carboxy-Terminal Tail of Polycystin-1, 2 years, $92,352
  • Wang Min, NIH, Inhibiting JNK: A New Anti-Inflammatory Strategy, 2 years, $1,059,124 *
  • Arie Mobley, NIH, Mechanisms of Embryonic Olfactory Sensory Neuron Axon Targeting, 2 years, $101,764
  • Shelby Montague, NIH, Translation of Olfactory Input into Behavioral Output in the Drosophila Larva, 3 years, $93,073
  • Walther Mothes, NIH, Targeting HIV Cell-to-Cell Transmission, 4 years, $2,218,363
  • Michael Nathanson, NIH, Silvio O. Conte Digestive Diseases Research Core Center, 5 years, $6,007,650 *
  • Lynda Odofin, NIH, Prevalence of Community-Acquired MRSA in Live Pigs and their Handlers, 2 years, $85,077 *
  • Stephanie O’Malley, NIH, Career Support and Mentoring of Interdisciplinary Alcohol Research, 5 years, $1,236,542
  • Charisse Orme, NIH, Role of TUG in the Formation of Insulin-ResponsiveGLUT4 Vesicles, 3 years, $114,132
  • Godfrey Pearlson, NIH, Genetic Architecture of Alcohol Misuse Candidate Endophenotypes, 2 years, $996,533 *
  • Margaret Pisani, NIH, Feasibility of Measuring Sleep in a Critical Care Environment, 2 years, $438,880 *
  • Saif Rathore, Agency for Healthcare Research and Quality/DHHS, Race and Cardiac Catheterization Use in the Setting of Acute Myocardial Infarction: Classifications, Associations, and Long-Term Outcomes, 14 months, $34,800
  • Carrie Redlich, Center for Construction Research and Training,Assessment and Prevention of Isocyanate Exposures in the Construction Industry, 1 year, $149,986; NIOSH/CDC/DHHS, Isocyanate Skin and Air Exposure: Assessment and Control, 4 years, $1,648,387
  • Scott Rivkees, NIH, Adenosinergic Mechanism of Intrauterine Growth Retardation, 2 years, $823,948 *
  • James Rothman, NIH, “Suspended” Bilayers: New Technology to Study the Dynamics of Membrane Structure and Function, 2 years, $969,272 *
  • Nenad Sestan, NIH, Transcriptional Atlas of Human Brain Development, 2 years, $9,889,558 *
  • Mark Shlomchik, NIH, Murine Memory B Cell Development and Function, 5 years, $2,833,059
  • Michael Simons, NIH, Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers, 2 years, $1,153,026 *
  • Jeffrey Sklar, NIH, The JAZF1 Gene and Type 2 Diabetes, 3 years, $1,076,754
  • Mehmet Sofuoglu, NIH, Sensitivity to Intravenous Nicotine: Genetic Moderators, 2 years, $379,824
  • Mark Solomon, NIH, Pseudosubstrate Inhibition of the Anaphase Promoting Complex, 2 years, $662,000
  • Sandra Springer, NIH, Alcohol Pharmacotherapies among Released HIV+ Prisoners, 5 years, $4,011,217
  • Vinod Srihari, NIH, Specialized Treatment Early in Psychosis (STEP): A Community Health Center–Based Cost-Effectiveness Study, 2 years, $749,840 *
  • Matthew State, NIH, Genomic Profiling and Functional Mutation Analysis in Autism Spectrum Disorders, 2 years, $2,245,837 *
  • Stephen Strittmatter, NIH, Yale Cellular Neuroscience, Neurodegeneration, and Repair (CNNRProgram, 2 years, $1,524,000 *
  • Matthew Strout, NIH, Regulation and Dysregulation of Antibody Diversification, 5 years, $872,100
  • Susumu Tomita, NIH, Genome-Wide Screening of Transmembrane Subunits of Ion Channels, 2 years, $1,000,000 *
  • Federico Vaca, NIH, Development and Crash Injury Risk in Adolescent Latino Males, 3 years, $436,867
  • Flora Vaccarino, NIH, Biological Correlates of Altered Brain Growth in Autism, 2 years, $1,987,576 *; NIH, Cellular and Genetic Correlates of Increased Head Size in Autism Spectrum Disorder, 2 years, $491,452; NIH, Injury and Recovery in Developing Brain, 5 years, $6,906,861
  • Neil Vasan, NIH, Structural Studies of the Exocyst, 4 years, $123,364
  • Stuart Weinzimer, NIH, Closed-Loop Effectiveness and Ambulatory Regimens (CLEAR), 3 years, $2,189,034
  • Robert Weiss, NIH, Targeted siRNA Nanotechnology for Intravesical Treatment of Urological Diseases, 22 months, $985,031 *
  • Li Wen, NIH, Effect of Diet and Commensal Bacteria on Diabetes Outcome in NOD Mouse, 2 years, $991,054 *
  • Kenneth Williams, NIH, Yale/NIDA Neuroproteomics Research Center, 5 years, $8,448,566
  • Stephanie Young, NIH, Novel Signaling between Striatal Neurons and Postnatal Neural Progenitors, 2 years, $51,192
  • Huiping Zhang, NIH, Association and Function of Opioid Receptor Gene Variants to Substance Dependence, 3 years, $786,849 *

Non-Federal

  • Kathleen Akgun, University of Washington, Risk, Severity, and Outcome of Bacterial Pneumonia in an HIV +/- Veteran Cohort, 10 months, $135,707 *
  • Joel Beckett, American Vascular Association, Effect of A Polyphenols in Olive Oil on Smooth Muscle Cell Proliferation, 4 months, $3,000
  • Richard Belitsky, Gilead Foundation, HAVEN Primary Care Clerkship, 1 year, $75,000
  • Michael Bloch, Trichotillomania Learning Center, Inc., Double-Blind, Placebo-Controlled Trial of N-Acetylcysteine for Childhood Trichotillomania, 1 year, $20,000
  • Donald Botta, CoolSpine, LLC., Intraventricular Cooling Catheter, 2 years, $153,659 *
  • Cynthia Brandt, Massachusetts General Hospital, Rare Cancer Genetics Registry, 2 years, $72,277 *
  • Robert Bruce, Liberty Community Service, Inc., Services in Supportive Housing, 1 year, $130,000
  • Matthew Burg, Columbia University, Comparison of Depression Interventions after Acute Coronary Symptoms, 10 months, $71,443 *
  • Thomas Carpenter, Thrasher Research Fund, Assessing Vitamin D Requirements: The Role of Vitamin D Binding Protein in the Response to Vitamin D Supplementation in Infants, 3 years, $417,736
  • Peter Charpentier, Hebrew Rehabilitation Center for the Aged,HRC/IFAR, 1 year, $8,742
  • Lauren Cohn, Tufts University, The Role of STAT3 in Allergic Inflammation and Airway Remodeling, 1 year, $18,215
  • Larry Davidson, Illinois Institute of Technology, Adherence and Empowerment: Service Participation and Meaningful Outcomes, 1 year, $196,796
  • Madhav Dhodapkar, Leukemia and Lymphoma Society, Combination Therapy Targeting Natural Killer T Cells, 3 years, $600,000
  • Maria Diuk-Wasser, University of Minnesota, Eco-epidemiology of Leptospirosis in Latin Americans: Understanding Transmission Dynamics in a Community, 1 year, $15,373
  • Wawrzyniec Dobrucki, Society of Nuclear Medicine Education and Research Foundation, Noninvasive Quantitative MicroSPECT/CT Assessment of Myocardial Angiogenesis and Remodeling Post-MI in Diabetic Rats Subjected to Therapy with Bi-Functional Angiotensin II Receptor Blocker, 1 year, $25,000
  • Donald Engelman, University of Rhode Island, PHLIP Nanotechnology Platform for Cancer Imaging and Therapy: Nanoscience and Nanotechnology in Biology and Medicine, 2 years, $215,450 *
  • Jorge Galán, Columbia University, Type III Secretion Antigen Delivery System Assembled in Non-Replicating Platform, 5 months, $155,509
  • Mark Gerstein, Brigham and Women’s Hospital, Analysis of Patterns of Structural Variation in the 1000 Genomes Data Set, 10 months, $170,445 *; Massachusetts Institute of Technology, NIH MODENCODE DAC GO Grant, 1 year, $140,000
  • Frank Giordano, Williams Syndrome Association, Williams Syndrome, 2 years, $320,000
  • Tina Goldsmith, Organization for Autism Research, Comprehension of Pretense in Young Children with Autism: The Development of Assessment and Teaching Techniques, 16 months, $2,000
  • Elena Grigorenko, King Faisal University, Etiological Bases of Giftedness, 3 years, $467,620
  • Ruth Halaban, Melanoma Research Alliance, Sequencing of the Melanoma Exome, Transcriptions and Epigenome, 3 years, $999,999
  • Lyndsay Harris, Breast Cancer Research Foundation, Biomarker Incubator to Define and Validate Predictors of Response to Paciltaxel and Trastuzimab, 1 year, $199,999
  • Robert Heimer, Biomedical Center, St. Petersburg, Russia,International Feasibility Study of Pharmacy-Based HIV Prevention: St. Petersburg, 9 months, $38,593; Duke University, Drug Policy, Incarceration, Community Reentry, and Race Disparities in HIV/AIDS, 10 months, $391,623; United Nations Population Fund, Developing an Evaluation Platform for UNFPA’s Y-PEER Projects, 9 months, $168,000
  • John Hwa, American Heart Association, Prostanoid Receptor Pharmacogenetics and Environmental Trace Metals, 28 months, $240,372
  • Karl Insogna, Dairy Management, Inc., The Impact of Protein Supplement on Bone Mass in Older Men and Women, 2 years, $109,975
  • Megan King, G. Harold and Leila Y. Mathers Charitable Foundation,Mechanical Communication between the Nucleus and the Cytoplasm, 3 years, $1,100,000
  • Michael Koelle, Merck/United Negro College Fund, 2009 UNCF Merck Undergraduate Science Research Scholarship Award, 1 year, $10,000
  • Richard Lifton, Columbia University, GWAS for IgA Nephropathy, the Most Common Form of Glomerulonephritis, 10 months, $344,355 *
  • Nils Loewen, American Glaucoma Society, Application for Mentoring for Advancement of Physician-Scientists (MAPSEnabling Award Program, 1 year, $10,000
  • Paul Lombroso, Institute for the Study of Aging, Screening for Inhibitors of STEP, 1 year, $138,600
  • Charles Lusk, G. Harold and Leila Y. Mathers Charitable Foundation,Connecting Chromatin to the Lumen: Making Pores in the Nuclear Envelope, 3 years, $1,100,000
  • Steven Marans, NewAlliance Foundation, Inc., Child Development Community Policing Program, 1 year, $5,000
  • Richard Marottoli, Research Foundation for Mental Hygiene, Health and Aging Policy Fellowship, 1 year, $30,000
  • Kathleen Martin, Flight Attendant Medical Research Institute, Effects of Secondhand Cigarette Smoke Exposure on Adiponectin, mTOR and Vascular Disease, 22 months, $216,000
  • Eric Meffre, Mount Sinai School of Medicine, Loss of B Cell Tolerance in Primary Immunodeficiencies, 1 year, $310,645 *
  • Leonard Milstone, TransDerm, Inc., Delivery of Biologically Active Nucleic Acids to Epidermal Cells, 2 years, $885,279 *
  • Marc Potenza, University of Minnesota, N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gambling, 1 year, $237,204 *
  • Peter Rabinowitz, Harvard School of Public Health, Chronic Occupational Noise, Stressors, and Susceptibility in Cardiovascular Illness, 1 year, $22,223
  • Harvey Risch, Fred Hutchinson Cancer Research Center, Barrett’s and Esophageal Adenocarcinoma Consortium Genetic Susceptibility Study, 1 year, $20,889
  • Alan Sartorelli, National Foundation for Cancer Research, Approaches to the Therapy of Leukemia, 3 years, $151,940
  • Margretta Seashore, Children’s Nat’l Medical Center, Longitudinal Studies for Urea Cycle Disorders, 6 months, $6,594; Children’s Research Institute, Longitudinal Studies for Urea Cycle Disorders, 5 years, $500,000
  • Sachin Shah, American Heart Association, Variations of Inpatient Spending and Patient Outcomes with Acute MI, 6 months, $11,000
  • Robert Sherwin, Columbia University, Hydrozyuera (HUUse in Sickle Cell Disease, 9 months, $79,087
  • Michael Simons, Fondation Leducq, Transatlantic Network on Therapeutic Arteriogenesis and Metabolism Modulation, 5 years, $936,220
  • Stephen Strittmatter, Alzheimer’s Association, Neuronal Receptor Mediating the Disease-Causing Effects of A-Beta Oligomers, 3 years, $200,000
  • Vinzenz Unger, Johns Hopkins University, Structural Biology of Copper Homeostasis, 1 year, $261,490
  • Tong Wang, University of Cincinnati, Apical Chloride/Bicarbonate Exchangers in Small Intestine and Kidney, 10 months, $41,843
  • Nadia Ward, Research Triangle Institute, Yale University GEAR UPPartnership Grant, 1 year, $24,000
  • Sherman Weissman, Stanford University, Mapping Transcription Factors Binding Sites in the Mouse Genome, 6 months, $48,102 *
  • Scott Woods, University of California, Los Angeles, Prevention Trial of Family Focused Treatment in Youth at Risk for Psychosis, 2 years, $150,597 *
  • Qin Yan, The V Foundation for Cancer Research, Roles of Histone Demethylase Retinoblastoma Binding Protein 2 in Cancer, 2 years, $200,000
  • Herbert Yu, Brigham and Women’s Hospital, Genome-Wide Association Study of Endometrial Cancer, 1 year, $126,628 *