Stephen M Strittmatter, MD, PhD
Vincent Coates Professor of Neurology and Professor of Neurobiology; Director, Cellular Neuroscience, Neurodegeneration and Repair
Departments & Organizations
Program in Cellular Neuroscience, Neurodegeneration and RepairBiological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development
Interdepartmental Neuroscience Program
Yale Medical Group
Neurobiology: Kavli Foundation
Neurology: Alzheimer's Disease/Dementia and Neuro-degenerative Disorders
Biography
Stephen M. Strittmatter earned his undergraduate degree from Harvard College, summa cum laude, in 1980. He completed M.D. and Ph.D. training at Johns Hopkins in 1986 with mentorship from Solomon H. Snyder, M.D. He then moved to Massachusetts General Hospital for a medical internship and an Adult Neurology residency. While at Massachusetts General Hospital, he worked as a Research Fellow with Mark Fishman, M.D., exploring the molecular basis of axonal guidance. After a year as Fellow, he served briefly as an Assistant Professor at Harvard Medical School before moving to Yale University in 1993.He is currently holds the Vincent Coates Professorship of Neurology and co-founded the Yale Program in Cellular Neuroscience, Neurodegeneration and Repair. His research on axonal growth during development and regeneration has been recognized by honors from the Ameritec Foundation, the John Merck Fund, the Donaghue Foundation, the McKnight Foundation, the Jacob Javits Award of the NINDS and the American Academy of Neurology.
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Education
- AB, Harvard College, 1980
- M.D., Johns Hopkins University, 1986
- Ph.D., Johns Hopkins University, 1986
Selected Publication
- Hu F, Padukkavidana T, Vægter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM. Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron. 68:654-667. (2010).
Latest Honor and Recognition
- Ameritec Foundation
Articles
March 2012
Heading off the ‘silent thief of sight’
About a decade ago, when Isobel Soukup went for a routine eye exam, her primary ophthalmologist discovered that the...
July/August 2010
A familiar voice speaks up for Alzheimer’s patients, research
It began with a sweatshirt. In December 2007, when Tony- and Emmy-Award-winning actor David Hyde Pierce appeared on...
July/August 2010
Building a case against an Alzheimer’s culprit
In 2009, a team from the lab of Stephen M. Strittmatter, M.D., Ph.D., reported in Nature that small amyloid beta (A-β)...
Jan/Feb 2010
‘Stimulus package’ grants saving jobs, building infrastructure, advancing research at Yale
The $787 billion American Recovery and Reinvestment Act of 2009 (ARRA), colloquially known as “the stimulus package,”...
May/June 2009
A protein’s surprise role in Alzheimer’s
In 1906, the German psychiatrist Alois Alzheimer first described the disease that now bears his name, noting that...
May/June 2009
A continuous infusion of philanthropy
According to family lore, Ralph Falk, M.D., a physician and surgeon who practiced in Boise, Idaho in the early to...
May/June 2008
A scientific assault on brain diseases
The School of Medicine is home to outstanding research programs in cell biology and neurobiology, and members of its...
Jan/Feb 2006
Restoring flexibility to heal broken brains
In early life, the brain is continually sculpted by stimuli from the outside world. But soon, most neural circuits...
Jan/Feb 2006
Neuroscientists target disorders of the brain and spinal cord
Neurodegenerative diseases, such as Alzheimer’s, Huntington’s and Parkinson’s, and injuries to the brain and spinal...
Oct/Nov 2005
Grants and contracts awarded to Yale School of Medicine
FederalVikki Abrahams, NIH, Innate Immune Responses of Trophoblasts in Pregnancy, 5 years, $1,375,632Anton Bennett,...
June/July 2005
Grants and contracts awarded to Yale School of Medicine
FederalKaren Anderson, NIH, A Novel Approach for Studying Transient Enzyme Intermediates, 4 years, $1,219,062Susan...
Aug/Sept 2005
Grants and contracts awarded to Yale School of Medicine
FederalGeorge Aghajanian, NIH, Psychotogenic Drug Action on Chemically Defined Neurons, 4 years, $931,200Thomas...
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