Grants and contracts awarded to Yale School of Medicine

September/October 2007


  • Nadia Abdala, NIH, Alcohol and HIV Risk Reduction in St. Petersburg, Russian Federation, 4 years, $2,757,715
  • Norrina Allen, Agency for Health Care Research and Quality (AHRQ), Geographic Patterns in Recurrent Stroke Rates by Gender and Race, 18 months, $37,519
  • Frederick Altice, Health Resources and Services Administration, Special Projects of National Significance, 4 years, $1,600,000
  • George Anderson, NIH, Neuroendocrine, Pharmacology, and Genetics Core Resource, 5 years, $1,620,365
  • Karen Anderson, NIH, Universal Technology for Profiling the Dynamics of Normal and Oncogenic Signaling, 2 years, $363,569
  • Amy Arnsten, NIH, Ionic and Second Messenger Basis of Stress-Induced Prefrontal Dysfunction, 5 years, $1,654,000
  • Andrew Bellemer, NIH, Mechanisms for Inhibition of Neurotransmitter Release by the G Protein Galphao, 3 years, $93,967
  • Jeffrey Bender, NIH, Molecular Models of Estrogen-Induced Vascular Protection, 6 months, $371,250
  • Zubin Bhagwagar, NIH, A Study of GABA and 5-HT Interactions to Test a Molecular Model of Vulnerability to Depression, 5 years, $904,796
  • Hilary Blumberg, NIH, Stress, Neurodevelopment and the Emergence of Addictive Behaviors in Adolescence, 5 years, $992,250
  • Michael Bracken, NIH, National Children’s Study, 5 years, $15,053,669
  • Elizabeth Bradley, Agency for Health Care Research and Quality (AHRQ), Hospital Strategies to Improve Outcome Performance, 4 years, $1,085,403
  • Ronald Braithwaite, NIH, A Computer Simulation of the Sub-Saharan HIV Pandemic That Can Estimate Benefit and Value from Alcohol Interventions, 5 years, $2,144,325
  • Matthew Burg, NIH, Reducing Vulnerability to ICD Shock Treated Ventricular Arrhythmias, 5 years, $2,929,047
  • Michael Cappello, NIH, Research Training in Pediatric Infectious Diseases, 5 years, $610,290
  • Harvey Chin, NIH, Defining Effects of Myosin VII Structure and Kinetics on Hereditary Deafness, 2 years, $81,944
  • Judy Cho, NIH, IBD Genetics Consortium Data Coordinating Center, 5 years, $5,703,845; NIH, Yale University IBD Genetics Research Center, 5 years, $1,858,550
  • Paul Cleary, Agency for Health Care Research and Quality (AHRQ), Consumer Assessment of Healthcare Providers and Systems, 5 years, $7,354,181
  • Lawrence Cohen, NIH, Scan of Protein Space for Optical Voltage Probes, 5 years, $5,049,153
  • David Cone, Centers for Disease Control and Prevention (CDC), E-Semble Virtual Reality Software for Mass Casualty Triage System, 1 year, $15,000
  • Joan Cook, NIH, Dissemination of Empirically Supported Psychotherapies, 2 years, $341,086
  • Michael Crair, NIH, Development and Plasticity at Thalamocortical Synapses, 5 years, $1,339,539
  • Kristina Crothers, NIH, Longitudinal Studies of HIV-Associated Lung Infections and Complications, 5 years, $3,964,897
  • Dianne Duffey, NIH, Mechanisms of ATF2 in Survival of Head and Neck Cancer, 1 year, $135,000
  • Jasmine Escalera, NIH, Activation of TRPA1 Irritant Receptors by Acrolein Fungal Toxicants, 3 years, $122,916
  • Andrew Flannery, NIH, Molecular Interactions Involved in Calcium-Regulated Phagocytosis, 3 years, $153,822
  • Terri Fried, NIH, Expanding Treatment Options for Older Persons, 5 years, $914,037
  • Jorge Galán, NIH, The Type III Secretion Effector Protein Interactome, 2 years, $454,395
  • Alison Galvani, NIH, Optional Influenza Vaccine and Population Adherence, 3 years, $625,925
  • Joel Gelernter, NIH, Alcohol Dependence Genetics in a Large Chinese Pedigree, 2 years, $345,280
  • Peter Glazer, NIH, Targeted Correction of the Human Beta-Globin Gene, 4 years, $1,648,410
  • Fred Gorelick, NIH, Exocrine Pancreatic Zymogen Activation, 5 years, $1,224,014
  • Shannon Gourley, NIH, Role of Amygdalostriatal CREB Activity in Persistent Depressive-Like Behavior, 2 years, $50,697
  • Traci Green, NIH, Substance Use, HIV Infection and Mortality in a Cohort of Aging Veterans, 2 years, $66,310
  • Carlos Grilo, NIH, Treatment of Binge Eating in Obese Patients in Primary Care, 5 years, $1,695,520
  • David Hiller, NIH, Mechanism of Peptidyl Transfer by the Ribosome Deduced by Kinetic Isotope Effects, 2 years, $96,472
  • Mark Horowitz, NIH, Control of Osteogenesis and Adipogenesis by EBF, 4 years, $1,283,082
  • Karl Insogna, NIH, Microcomputed Tomography Device (Scanco Micro CT35), 1 year, $233,348
  • Paul Ivancic, Nat’l Center for Injury Prevention and Control (NCIPC), Prevention of Neck Injuries in Older Adults during Rear Motor Vehicle Collisions, 3 years, $808,284
  • Leslie Jacobsen, NIH, Prenatal Cocaine Exposure: Studies of Brain Function, 20 months, $455,153
  • Insoo Kang, NIH, Investigating Membrane-Associated T Cell Receptor Signaling in Human CD8+ T Cell Subsets, 2 years, $270,600; NIH, Aging and IL-7-Mediated CD8+ T Cell Survival, 5 years, $1,695,350
  • Kenneth Kidd, Dept. of Justice (U.S.), Population Genetics of SNPs for Forensic Purposes, 18 months, $911,125; Nat’l Science Foundation (NSF), ALFRED: A Resource for Research and Teaching Human Evolution, 2 years, $248,516; Nat’l Science Foundation (NSF), ALFRED: A Resource for Research and Teaching Human Evolution, 3 years, $370,691
  • Harlan Krumholz, NIH, Young Women with Acute Myocardial Infarction, 4 years, $9,848,211
  • John Krystal, NIH, Cortical GABA Function in Alcoholism, 5 years, $3,318,900
  • Gary Kupfer, NIH, Functional Characterization of the Fanconi Anemia Core and D2 Complexes, 3 years, $1,008,219
  • Daeyeol Lee, NIH, Stress, Prefrontal Cortex, and Decision Making, 5 years, $1,240,500
  • John Leventhal, NIH, Integrating Well-Woman and Well-Baby Care to Improve Parenting and Family Wellness, 2 years, $454,605
  • Paul Lizardi, NIH, Probes for Detection of DNA Accessibility in Chromatin, 3 years, $1,129,191
  • Charles Lockwood, NIH, Progestin Effects on Uterine Hemostatsis and Angiogenesis, 5 years, $2,163,672
  • Carolyn Mazure, NIH, Interdisciplinary Research Education, 5 years, $857,917
  • Sherry McKee, NIH, Modeling Stress-Precipitated Smoking Lapse for Medication Development, 5 years, $1,240,500
  • Diane McMahon-Pratt, NIH, Integrated Functional Genomics: On the Road to Leishmaniasis Control, 1 year, $4,000; NIH, Multidisciplinary Parasitology Training Program, 5 years, $1,176,943
  • Ewan McNay, NIH, Insulin in the Hippocampus: Memory Enhancement and Impact of Type 2 Diabetes, 5 years, $1,529,950
  • Yorgo Modis, Dept. of the Army, The Structural Basis of Pathogen Recognition by Receptors of the Innate Immune System, 1 year, $178,655
  • Alexander Neumeister, NIH, Norepinephrine Transporter Imaging in Alcohol Dependence and Obesity, 5 years, $1,240,500
  • Laura Niklason, NIH, Enabling Strategies for Growing Collagenous Tissues, 4 years, $2,061,843
  • Stephanie O’Malley, NIH, Naltrexone for Heavy Drinking in Young Adults, 5 years, $3,062,762
  • Godfrey Pearlson, NIH, Bipolar and Schizophrenia Consortium for Parsing Intermediate Phenotypes, 4 years, $3,195,446
  • Joao Pedra, Centers for Disease Control and Prevention (CDC), Critical Role of the ASC/Caspase-1 Pathway in Tick-Borne Rickettsiosis, 3 years, $450,000
  • Marc Potenza, NIH, fMRI of Stress and Self-Control in Smoking and Obesity, 5 years, $1,002,822
  • Enrique Pouget, NIH, Male-Female Sex Ratio and Risk for HIV/STI Among African-American Women, 1 year, $40,972
  • Ann Rasmusson, NIH, GABAergic Neurotransmission in PTSD, 18 months, $356,980
  • Jill Reiter, Dept. of Defense (U.S.), Soluble EGFR Isoforms in Cell Growth Control, 1 year, $119,763
  • Bruce Rounsaville, NIH, Clinician Scientist Training in Substance Abuse Research, 5 years, $4,840,939
  • Mehran Sadeghi, NIH, Molecular Imaging of Vascular Remodeling, 5 years, $1,622,500
  • David Schatz, NIH, Interdisciplinary Immunology Training Program, 5 years, $2,816,856
  • Richard Schottenfeld, NIH, Drug Counseling and Abstinent-Contingent Take-Home Buprenorphine in Malaysia, 5 years, $1,614,643
  • Jody Sindelar, NIH, Stressors and Their Impact on Health-Related Addictions: Smoking, Drinking, Body Mass Index, 5 years, $1,211,112
  • Rajita Sinha, NIH, Human Subjects Core: Protocols, Statistics, and Collaborative Method Development, 5 years, $2,962,253; NIH, ORWH: SCOR on Sex and Gender Factors Affecting Women’s Health, 5 years, $5,255,014; NIH, Interdisciplinary Research on Stress, Self-Control and Addiction, 5 years, $5,742,328
  • Robert Soufer, NIH, Neurobehavioral Correlates of Mental Stress Ischemia, 5 years, $2,397,801
  • Julie Staley-Gottschalk, NIH, Neuroreceptor Imaging of Tobacco Smokers, 5 years, $504,467
  • Jane Taylor, NIH, Stress-Induced Compulsive Behaviors: CRF Regulation, 5 years, $1,057,800
  • Derek Toomre, NIH, Novel TIRF Microscopy for Analyzing Trafficking and Signaling at the Cell Cortex, 5 years, $2,481,250
  • Xiao-Jing Wang, NIH, Recurrent Neural Circuit Basis of Time Integration and Decision Making, 5 years, $1,860,938
  • Joanne Weidhaas, NIH, Defining the Genetic Basis of the Radioresponse Using a C. elegans Tissue Model, 5 years, $555,660
  • Stuart Weinzimer, NIH, Yale Study of Closed-Loop Automated Glucose Control for Hypoglycemia Prevention, 5 years, $1,197,606
  • John Wysolmerski, NIH, The Effect of PTHrP during Lactation, 4 years, $1,308,611
  • Huiping Zhang, NIH, Association and Function of Opioid Receptor Gene Variants to Substance Dependence, 2 years, $176,324
  • Zhengdong Zhang, NIH, Gene Regulation in Metastasis and New Methods to Analyze Its Microarray Profiles, 2 years, $178,496
  • Hongyu Zhao, Nat’l Science Foundation (NSF), Collaborative Research: A General Framework for High-Throughput Biological Learning: Theory Development and Applications, 3 years, $359,997

  • Vikki Abrahams, Lupus Foundation of America, Mechanisms of Antiphospholipid Antibody-Induced Pregnancy Complications in Patients with APS, 1 year, $60,000
  • Anna Cali, Thrasher Research Fund, Intrahepatic Fat Accumulation, Total and HMW Adiponectin, and the Metabolic Syndrome in Obese Youth, 1 year, $26,750
  • Jodi Carlson, Animal Welfare Institute, Development of a Booklet on the Pair Housing of Macaques, 6 months, $3,000
  • Sreeganga Chandra, American Parkinson’s Disease Association, Inc., Delineating the Physiological Function of Synucleins, 1 year, $50,000
  • Lauren Cohn, Juvenile Diabetes Research Foundation Int’l, Inhaled Insulin and Lung Immunity, 1 year, $110,000
  • Miriam Delphin, Advocates for Human Potential, Inc., Shared Decision Making, 6 months, $10,000
  • Michael DiGiovanna, The Breast Cancer Research Foundation, Activated HER2 as a Predictor of Therapeutic Response and as a Target in Novel Combination Therapies, 1 year, $100,000
  • Yu-Shin Ding, Pfizer Inc, Feasibility Study into NET Occupancy Determination with PET Radioligand [C-11]MRB([C-11]MeNER), 9 months, $212,195
  • Ronald Duman, Sepracor Inc., Influence of Eszopiclone on Chronic Unpredictable Stress (CUS): Blockade of the Anti-Neurogenic and Anhedonic Effects of CUS, 1 year, $148,575
  • Richard Edelson, Union Mutual Foundation, Investigations in Transimmunization, 1 year, $25,000
  • Terri Fried, Robert Wood Johnson Foundation, Evolving Toward Effective and Efficient Health Care Decision Making Based on Health Outcomes Priorities Among Adults with Multiple Health Concerns, 2 years, $224,986
  • John Geibel, AstraZeneca AB, Zinc is a Potent Inhibitor of Acid Secretion, 1 year, $250,000
  • Mark Gerstein, Wellcome Trust, Integrated Human Genome Annotation: Generation of a Reference Gene Set, 9 months, $177,403
  • Jeffrey Gruen, JS Genetics, Molecular Diagnosis of Dyslexia, 6 months, $36,409
  • Lyndsay Harris, The Breast Cancer Research Foundation, Biomarker Incubator to Define and Validate Predictors of Response to Paclitaxel and Trastuzumab, 1 year, $223,911
  • Kevan Herold, Juvenile Diabetes Research Foundation Int’l, Preclinical Studies of Anti-CD3 mAb and IL-1Ra, 1 year, $110,280; University of Michigan Health System, Brehm Coalition Award, 2 years, $500,000
  • Pei Hui, Third Wave Technologies, Inc., A Study to Evaluate the Analytical and Clinical Performance of the Invader HPV Reagents, 1 year, $47,190
  • Shuta Ishibe, American Society of Nephrology, Role of the Met Receptor in Kidney Development and Repair, 2 years, $200,000
  • Robert King, Tourette Syndrome Association, Inc., A Genetic Linkage Study of GTS, 1 year, $140,356
  • Steven Kleinstein, Mount Sinai School of Medicine, Modeling Viral Immunity and Antagonism, 3 years, $794,542
  • Jeffery Kocsis, Nat’l Multiple Sclerosis Society, Therapeutic Potential of Cellular Transplantation into a Focal Model of EAE, 3 years, $463,694
  • Themis Kyriakides, Georgia Institute of Technology, Regenerative Acellular Biomaterials Derived from Embryonic Stem Cells, 2 years, $21,009
  • Paul Lombroso, The Institute for the Study of Aging, Inc., Screening for Inhibitors of STEP, 1 year, $100,000
  • Mark Mamula, L2 Diagnostics, LLC, EGFR Peptides as Vaccines in Anti-Tumor Immunity, 18 months, $96,144
  • Rory McCrimmon, Juvenile Diabetes Research Foundation Int’l, Restoring Hypoglycemia Counterregulation in T1DM, 3 years, $495,000
  • Thomas McMahon, Columbia University-Teachers College, Maternal Drug Use, Psychopathology and Child Adaptation, 5 years, $889,255
  • Gil Mor, The Johns Hopkins University, Multiplex Serum Biomarker for Ovarian Cancer, 2 years, $267,985
  • Angus Nairn, Brown University, Structural and Functional Analysis of Signaling Proteins in Dendritic Spines, 1 year, $23,703
  • Alexander Neumeister, Nat’l Alliance for Research on Schizophrenia and Depression, Contribution of Early Life Trauma on Serotonin 1b Receptor Expression in Depression, 2 years, $99,040
  • Karin Provost, American Thoracic Society, Airway Epithelial Regulation of Allergic Airway Response, 1 year, $50,000
  • David Reiss, Oregon Social Learning Center, Early Growth and Development Study, 5 years, $292,366
  • Scott Rivkees, JS Genetics, Newborn Screening for Sex Chromosomes Disorders, 1 year, $109,379
  • Gerard Sanacora, Nat’l Alliance for Research on Schizophrenia and Depression, The Effect of Stress and Antidepressants on Amino Acid Neurotransmission and Glial Cell Function, 2 years, $98,952
  • Alan Sartorelli, Nat’l Foundation for Cancer Research, Development of a Rapid Simple Quantitative Assay for AGT, the Resistance Protein for Cloretazine and Other 06-Guanine Targeting Drugs, for the Selection of Patients with a High Probability of Response, 1 year, $75,000
  • Heather Scobie, Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation, Defining the Functional Interface Between Campylobacter jejuni and its Mammalian Host Cells, 3 years, $140,000
  • Stephen Strittmatter, F.M. Kirby Foundation, Inc., Stroke Research Project, 1 year, $100,000
  • Susumu Tomita, Alfred P. Sloan Foundation, Research Fellowship, 2 years, $90,000
  • Fred Volkmar, The Nancy Lurie Marks Foundation, Undergraduate Education in Autism, 2 years, $35,051
  • Anne Williamson, ITN Energy Systems, Inc., Wireless Multimodal Brain Monitoring, 1 year, $29,223