Michael J Caplan, PhD, MD
C. N. H. Long Professor of Cellular and Molecular Physiology and Professor of Cell Biology; Chair, Cellular and Molecular Physiology

Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and PhysiologyCell Biology
Cellular & Molecular Physiology: Membrane Proteins - Pumps and Transporters | Membrane Protein Sorting and Trafficking | Epithelial Transport of Ions and Solutes | Organ Physiology | Physiology of Human Disease | Graduate Program in Cellular and Molecular Physiology(
Liver Center)
Biography
Michael J. Caplan received his bachelors degree from Harvard University and his M.D. and Ph.D. degrees from Yale University in 1987. He joined Yale's Department of Cellular and Molecular Physiology as a faculty member in 1988, and is currently the C.N.H. Long Professor of Cellular and Molecular Physiology and Cell Biology.He has received fellowships from the Helen Hay Whitney Foundation, the David and Lucille Packard Foundation for Science and Engineering, and a National Young Investigator Award from the National Science Foundation. He has also received the Young Investigator Awards from the American Physiological Society and the American Society of Nephrologists.
His work focuses on understanding the ways in which kidney cells organize and maintain their unique structures. His laboratory also studies the mechanisms responsible for Autosomal Dominant Polycystic Kidney Disease, and is working to identify targets for new therapies.
Education
- M.D., Yale University, 1987
- Ph.D., Yale University, 1987
Selected Publication
- Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J Biol Chem, 278:36786-36793, 2003.
Latest Honor and Recognition
- Charles W. Bohmfalk Teaching Prize, Yale School of Medicine
Articles
May/June 2010
Grants and contracts awarded to Yale School of Medicine
FederalSerap Aksoy, NIH, Tsetse Fecundity Reduction for Tryopanosomiasis Control, 5 years, $2,064,820Karen Anderson,...

July/August 2010
Expert on causes of kidney disease will lead physiology department
Michael J. Caplan, M.D., Ph.D., who studies how membrane proteins find their proper location on the cell surface, and...

December 2010
Medical school’s mentors ‘pay it forward’
Though few of the hundreds of busy people who pass through the doors of Sterling Hall of Medicine each day notice the...

March/April 2009
Protein sorting, kidney disease are interests of Long Professor
Michael J. Caplan, M.D., Ph.D., professor of cellular and molecular physiology and of cell biology, has been named the...
July/August 2006
Biology, medicine unite in new grad initiative
Biology and medicine have been tightly intertwined since antiquity, but the bond between the two has loosened over the...

June/July 2005
Grants and contracts awarded to Yale School of Medicine
FederalKaren Anderson, NIH, A Novel Approach for Studying Transient Enzyme Intermediates, 4 years, $1,219,062Susan...



