Grants and contracts awarded to Yale School of Medicine

September/October 2006


  • Maria Teresa Baquero, Department of the Army, Microtubule-Associated Protein Expression and Predicting Taxane Response, 3 years, $96,120
  • Clifford Bogue, NIH, Hex—A Homeobox Gene Essential for Liver Development, 2 years, $432,300
  • Lloyd Cantley, NIH, Stem Cells in Organ Maintenance and Repair, 1 year, $12,000
  • Thomas Carpenter, NIH, Center of Research Translation Program (CORT), 5 years, $8,213,600
  • Kathleen Carroll, NIH, Computer-Based Training for Cognitive Behavioral Therapy, 3.5 years, $1,407,143
  • Junjie Chen, NIH, Study of the Role of DNA Damage Reponses in Tumorigenesis and Senescence, 4.5 years, $1,265,587; NIH, Analysis of BRCA1 Function in DNA Repair, 4.5 years, $1,334,551; Department of Defense, Genomic Instability and Breast Cancer, 4 years, $825,000
  • Yung-Chi Cheng, NIH, Nucleoside Analogs as Anticancer Compounds, 4.5 years, $1,495,498
  • Judy Cho, NIH, Mapping Chromosome 3q Inflammatory Bowel Disease, 3 years, $867,270
  • Jimmy Choi, NIH, Motivation and Learning in Schizophrenia, 1 year, $56,199
  • Vladimir Coric, National Geospatial-Intelligence Agency, Efficacy of Forensic Analysis in Detecting Deception During High Stress Situations, 1 year, $119,632
  • Kelly Cosgrove, NIH, Brain Imaging of Sex Differences in Tobacco Smokers, 5 years, $893,700
  • Joseph Craft, NIH, Genetic Analysis of T Cells in Lupus, 5 years, $1,818,504
  • Alan Dardik, NIH, Flow Responses to Carotid Angioplasty, 4.5 years, $665,550
  • Christopher DeFeo, NIH, Structure and Function of the Human Copper Transporter, 2 years, $66,060
  • James Duncan, NIH, LV Strain Quantification from 4D Echocardiography, 4.5 years, $7,244,829
  • Brian Elbel, Agency for Health Care Research and Quality, Choice Sets and Consumer Selection of Health Plans,1 year, $32,400
  • Julia Etchin, Department of the Army, Molecular Basis for BRCA2-Mediated DNA Repair and Breast Tumor Supression, 3 years, $97,200
  • Leigh Evans, Agency for Health Care Research and Quality, Simulation Training for Ultrasound Guided Central Venous Catheter Insertion, 2 years, $532,681
  • John Forrest, NIH, Yale Predoctoral Clinical Research Training Program, 1 month, $581,683
  • Jorge Galán, NIH, Predoctoral Training Program in Microbial Pathogenesis, 5 years, $1,061,569
  • Joel Gelernter, NIH, Genetics of Cocaine Dependence, 4 years, 7 months, $5,980,328
  • Harindarpal Gill, NIH, NBCe1 and n1: Crystal Structure Determination, 2 years, $85,989
  • Charles Greer, NIH, Mechanisms of Aging in the Olfactory System,5 years, $6,652,339
  • Mridu Gulati, National Institute for Occupational Safety and Health, Longitudinal Study of Respiratory Function in Aluminum Smelter Workers, 3 years, $291,600
  • Noam Harel, NIH, Nogo’s Role in Intracellular Trafficking, 4.5 years, $782,316
  • George Heninger, NIH, Substance Abuse Education for Medical Students, 2.5 years, $652,532; NIH, Clinical and Basic Neurobiology of Nervous System Diseases, 2 years, $134,362
  • Henry Huang, NIH, New PET Radioligand for Serotonin Transporter, 2 years, $714,183
  • Karl Insogna, NIH, Impact of a Protein Supplement on Bone Mass in Older Women, 4 years, $1,876,418
  • Sven-Eric Jordt, NIH, TRPA1 Channels in Sensory Neurons as Targets for Environmental Irritants, 5 years, $2,390,822; NIH, Sensory Neural Mechanisms of Pulmonary Agent and Vesicant Toxicity, 4.5 years, $2,446,733
  • Amy Justice, NIH, Veterans Aging Cohort Study, 5 years, $13,928,272
  • Joan Kaufman, NIH, Genetic and Environment Modifiers of Child Depression, 4.5 years, $1,858,595
  • Trace Kershaw, NIH, HIV/STD Risk Among Young Expectant Fathers: Relationship Attachment and Transition, 4.5 years, $2,537,672
  • Michael Krauthammer, NIH, Text Mining as a Translational Tool in Biomedicine, 3 years, $439,857
  • Daeyeol Lee, NIH, Cortical Mechanisms of Sequence Learning, 7 months, $303,729
  • Chiang-Shan Li, NIH, Imaging Inhibitory Control in Cocaine Dependence, 1 year, $208,800
  • Haifan Lin, NIH, Regulation of Germline Stem Cell Division in Drosophila, 1 year, $94,875
  • Brett Lindenbach, NIH, Hepatocellular Carcinoma: Targeting HVC Replication, 3.5 years, $613,302
  • Xiaomei Ma, NIH, Myelodysplastic Syndromes: Previous Exposures, Survival, and Quality of Life, 5 years, $698,600
  • Robert Malison, NIH, Genetics of Opioid Dependence in a Hmong (Thai) Isolate, 2 years, $553,320
  • Irvin Modlin, NIH, Molecular Strategies to Define Carcinoids and Rationalize Surgical Intervention, 3.5 years, $1,173,350
  • Laura Niklason, NIH, Biological Vascular Grafts, 4 years, 7 months, $3,477,864
  • Jordan Pober, NIH, Chronic DTH and IFN-gamma in Human Graft Arteriosclerosis, 5 years, $11,635,495
  • Vazhaikkurichi Rajendran, NIH, Role of IK Channels in Rat Distal Colon, 5 months, $1,614
  • Faye Rogers, NIH, Altered Helical Structures: Repair and Induction of Genomic Instability, 3 years, $445,161
  • Robert Sherwin, NIH, Clinical and Translational Science Award TL1, 4.5 years, $57,330,994
  • Arthur Simen, NIH, Epigenetic Factors in Stress-Enhanced Acquisition of Cocaine Self-Administration, 2 years, $330,083
  • Dennis Spencer, NIH, Origin of Extracellular Glutamate in Human Temporal Lobe Epilepsy, 3.5 years, $2,056,128
  • Matthew State, NIH, The Role of SLITRK1 in Tourette and Related Disorders, 5 years, $2,217,291
  • Rebecca Sweet, NIH, Autoimmune Memory Development and Maintenance, 2.5 years, $127,392
  • Fred Volkmar, NIH, Autism and Related Disorders: Development and Outcome, 5 years, $5,906,778
  • Kathleen Wilson, Department of the Army, The Roles of NFBD1, 53BP1, and BRCA1 in the DNA Damage Response, 3 years, $96,746
  • Dianqing Wu, NIH, Wnt Signaling and Bone Biology, 3 years, 6 months, $1,521,756; NIH, Molecular Function of Chemoattractant-Mediated Signaling, 3 years, 6 months, $1,776,906

  • Ali Abu-Alfa, Genzyme, Genzyme–Yale Educational Conferences, 7 months, $20,700
  • Diana Beardsley, University of Massachusetts, Prevention of the Complications of Bleeding Disorders, 1 year, $23,189
  • Henry Binder, Christian Medical College Hospital, Comprehensive Studies of a New Improved Oral Rehydration Solution for Diarrheal Disease, 1 year, $69,250
  • Hilary Blumberg, National Alliance for Research on Schizophrenia and Depression, Frontal Markers of Vulnerability and Resilience to Bipolar Disorder, 2 years, $100,000
  • James Boyer, Mount Desert Island Biologic Laboratory, Development of a Comparative Toxicogenomics Database, 5 years, $22,890
  • Michael Bracken, Johns Hopkins University, Genome-Wide Association Studies of Asthma in Populations of African Descent, 3 years, $188,881
  • David Brissette, Physician Assistant Education Association, Physician Assistants as Medicine Hospitalists, 1 year, $4,972
  • Richard Bucala, Bay Pines Foundation, Release of MIF Protein Complexes in Vivo: Response to Inflammation, 11 months, $13,272
  • David Calderwood, U.S. Israel Binational Science Foundation, Cytoplasmic Regulation of LFA-1 Assemblies Underlying Lymphocyte Adhesion Transmigration and Immune Cell Recognition: The Talin Link, 4 years, $71,564
  • Michael Carrithers, National Multiple Sclerosis Society, T Lymphocyte Surveillance and the Neuroprotective Barriers in Health and Disease, 3 years, $415,719
  • Owen Chan, Juvenile Diabetes Research Foundation International, Role of GABA in Modulation of Counterregulatory Responses to Hypoglycemia, 3 years, $89,308
  • Junjie Chen, Susan G. Komen Breast Cancer Foundation, Understanding the Tumor Suppression Function of BRCA1, 1 year, 7 months, $120,080; Mayo Clinic of Rochester, Mayo Clinic Breast Cancer SPORE, 1 year, $178,326
  • Paul Cleary, Harvard University, National Implementation of Medicines Consumer Assessment of Healthcare Providers and Systems, 7 months, $117,978
  • Michael DiGiovanna, Breast Cancer Research Foundation, Activated HER2 as a Predictor of Therapeutic Response and as a Target in Novel Combination Therapies, 1 year, $249,263
  • Wawrzyniec Dobrucki, Juvenile Diabetes Research Foundation International, Noninvasive Assessments of Myocardial and Peripheral Therapeutic Angiogenesis in Animal Models of Type-1 Diabetes Mellitus, 3 years, $88,214
  • Glen Farr, American Cancer Society, Regulation of Na,K-ATPase Function by the Tetraspanin Protein CD81, 3 years, $138,000
  • Simmie Foster, United Negro College Fund, An Adaptive Response of the Innate Immune System, 2 years, $52,000
  • Gerald Friedland, AIDS Project Hartford, HIV Prevention Intervention Research with HIV positive Incarcerated Populations, 2 years, $123,048
  • Alison Galvani, James S. McDonnell Foundation, Developing and Applying Game Theoretic Vaccination Models with Psychological Data, 6 years, $442,905
  • Alexandria Garino, Physician Assistant Education Association, Improving Clinical Anatomy Recall and Spatial Reasoning in Physician Assistant Students,1 year, $2,500
  • Walter Gilliam, Child Health & Development Institute of Connecticut, Preschool Mental Health Climate Scale: A Tool for Preschool Mental Health Consultants and Other Professionals, 1 year, $50,000
  • Bryan Hains, Dana Foundation, Neuroimmune Modulation of Chronic Pain after Spinal Cord Injury, 2 years, $200,000
  • Robert Heimer, Gilead Foundation, Evaluating the Effects of Expanded Hours for Syringe Exchange Programs in Connecticut, 1 year, $25,000; Gilead Foundation, Pilot Intervention Research: Brief Care-Based HIV Prevention for Newly Diagnosed Men,1 year, $25,000
  • Erica Herzog, Edward Mallinckrodt, Jr. Foundation, Mechanisms of Bone Marrow: Epithelial Fusion in the Murine Lung, 3 years, $210,000
  • Amy Justice, University of California, San Francisco, Treatments for Complex Patients in New Settings, 1 year, $24,800
  • Mark Mamula, L2 Diagnostics, LLC, Modified HER-2 Tumor Antigens for Vaccination in Cancer, 11 months, $264,075
  • Aaron McGee, Burroughs Wellcome Fund, Inhibition of Plasticity in the Adult Central Nervous System by Nogo-66 Receptor Signaling, 5 years, $500,000
  • Haiying Meng, International Dyslexia Association, A Deletion in Intron 2 of DCDC2 Gene Regulates Protein Expression in Developmental Dyslexics, 1 year, $10,000
  • Yorgo Modis, L2 Diagnostics, LLC, Broad Spectrum Therapeutic Human Antibodies for Dengue Virus Infections, 1 year, $77,122; L2 Diagnostics, LLC, Antivirals Targeting Flavivirus Envelope Proteins, 1 year, $153,384
  • Kitt Petersen, Novartis Pharmaceuticals, Regulation of Muscle PDH Flux in Different Populations, 9 months, $202,010
  • Marc Potenza, University of Maryland at Baltimore, Genetic Contributions to Adolescent HIV Risk Behavior, 1 year, $28,655
  • Joseph Santos-Sacchi, Stanford University, New Technologies for Investigation of the Hair Cell Afferent Fiber Synapse, 1 year, $74,587
  • Gerald Shadel, American Federation for Aging Research, Mouse Models of Aging and Age-Related Pathology via Mitochondrial DNA Transformation, 1 year, $124,296
  • Wei-Xing Shi, National Alliance for Research on Schizophrenia and Depression, Prefrontal Control of DA Neurons in the VTA, 2 years, $100,000
  • Gerald Shulman, Medical College of Georgia, Coordinating and Bioinformatics Unit for the Mouse Metabolic Phenotyping Center, 5 years, $511,500
  • William Sledge, Eli Lilly and Company, Recovery Guide Treatment Program for Recurrent Psychiatric Hospitalization, 1 year, $99,193
  • Stefan Somlo, Plexxikon, Graft Inhibitors in Polycystic Kidney Disease, 1.5 years, $89,542; Icagen, Icagen Research Agreement, 1 year, $41,214
  • Scott Strobel, Howard Hughes Medical Institute, Bioprospecting for Natural Products in the World’s Rainforests: An Undergraduate Science Expedition, 4 years, $1,000,000
  • Fattaneh Tavassoli, Calibrant Biosystems, Breast Cancer Proteome via Laser-Free Microdissection and Gemini Technologies, 2 years, $37,196
  • Terence Trow, CoTherix, Educational Grant Agreement, 1 year, $5,000
  • Ping Wang, American Heart Association (Heritage Affiliate), Role of PLC-beta3 in the Initiation and Progression of Atherosclerosis, 1.5 years, $70,000
  • Dianqing Wu, University of Connecticut, Vascular Remodeling: Macrophage/Monocyte Signaling in Vascular Pathophysiology, 8 months, $148,873; University of Connecticut, Polarity in Networks and Pathways: The Study of Neutrophil Polarity, 7 months, $70,307
  • Zhinan Yin, Amino UP Chemical, AHCC Reduces Chemotherapy Side Effects, 1 year, $19,800
  • Yufeng Zhou, U.S. Israel Binational Science Foundation, Activation Gating of Potassium Channel Pores: A Unifying Mechanism Controlled by Hydrophobic Interactions, 4 years, $19,205