Thomas A Steitz, PhD
Sterling Professor of Molecular Biophysics and Biochemistry and Professor of Chemistry; Investigator, Howard Hughes Medical Institute

Departments & Organizations
Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: DNA Dynamics; Drug Design, Discovery and Mechanism; RNA Catalysis and Ribonucleoprotein Machines; Transcriptional Regulation; crystallography, NMR, mass spectrometry, cryo-electron...facultyStructural Biology
Global Health Initiative: Infectious Diseases | Tuberculosis
Molecular Biophysics and Biochemistry: Cell Cycle and Transcriptional Regulation | DNA Replication and Repair | RNA Biology | Structural Biology
Biography
Prof. Thomas Steitz received a B.A. degree in chemistry from Lawrence College in Appleton, Wisconsin, and a Ph.D. degree in molecular biology and biochemistry from Harvard, with William Lipscomb. After a postdoctoral year at Harvard, he moved to the Medical Research Council Laboratory of Molecular Biology in Cambridge, England, to work as a Jane Coffin Childs fellow with David Blow. He next joined the Yale faculty, where he has remained, except for sabbatical work with Klaus Weber in Göttingen, Germany; Aaron Klug at Cambridge; John Abelson at the California Institute of Technology; and Thomas Cech and Olke Uhlenbeck at the University of Colorado. He has received the 2009 Nobel Prize in Chemistry, the Pfizer Prize from the American Chemical Society, the Lewis S. Rosenstiel Award for distinguished work in basic medical sciences, the 2001 Newcomb Cleveland Prize from the American Association for the Advancement of Science, the Lawrence University Lucia R. Briggs Distinguished Achievement Award, the 2006 Keio Medical Science Prize, and the 2007 Gairdner International Award. Dr. Steitz is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. He was recently elected a fellow of the American Association for the Advancement of Science.Education
- BA, Lawrence College, 1962
- Ph.D., Harvard University, 1966
Selected Publication
- Bailey, S., Wing, R.A., and Steitz, T.A. (2006). The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Cell 126:893-904.
Latest Honor and Recognition
- Nobel Prize in Chemistry (2009), The Royal Swedish Academy of Sciences
Articles

July/August 2011
Nobelist is elected as a member of world’s oldest scientific society
Thomas A. Steitz, Ph.D., Sterling Professor of Molecular Biochemistry and Biophysics, Howard Hughes Medical Institute...

Jan/Feb 2010
Steitz in Stockholm
On December 10, in the elegant and festive setting of the Stockholm Concert Hall, King Carl XVI Gustaf of Sweden...

Nov/Dec 2009
Supporting Medical Education
Almost a century ago, John W. Sterling, of the Yale College Class of 1864 (right), ably demonstrated the ability of one...

Nov/Dec 2009
The tiniest scale yields the biggest prize
A telephone ringing before daybreak is unlikely to appear on anyone’s list of favorite sounds, but for Thomas A....

Nov/Dec 2007
Structural biologist wins top science prize
In a ceremony at the Four Seasons Hotel in Toronto, Canada, on October 25, Yale scientist Thomas A. Steitz, Ph.D.,...

Nov/Dec 2007
New AAAS Fellows
Six biomedical scientists and educators at Yale have been named as Fellows of the American Association for the...

Jan/Feb 2007
Biologist cited for structural insights into action of antibiotics
In a ceremony and commemorative symposium held at Keio University in Tokyo in November, Thomas A. Steitz, Ph.D.,...

July/August 2006
New look at how resistant bugs dodge drugs
Yale biologists have opened a new front in the war on antibiotic-resistant bacteria by creating the first...


