Grants and contracts awarded to Yale School of Medicine

January/February 2007


  • Roland Baron, NIH, From Adhesion to Bone Resorption: The Role of Dynamin in Osteoclasts, 5 years, $1,777,602
  • Alfred Bothwell, NIH, Revascularization of Islets to Treat Type 1 Diabetes, 2 years, $412,792
  • William Bradley, NIH, Adhesion-Dependent Inhibition of RhoA through Arg Tyrosine Kinase and p190RhoGAP, 3 years, $91,629
  • Suzanne Cassel, NIH, Role of Lung Inflammation in Th2 Priming, 5 years, $492,480
  • Junjie Chen, NIH, Analysis of 53BP1 Function in DNA Damage Signaling Pathway and Tumorigenesis, 4 years, $1,551,712
  • Kevin Collins, NIH, Heterotrimeric G-Protein Regulation of Neurotransmission in C. elegans, 3 years, $141,318
  • Michael Crair, NIH, Mechanisms of Visual Map Development, 2.5 years, $779,670
  • Isabelle Derre, NIH, RNAi Screen to Identify Host Factors Involved in Chlamydia Pathogenesis, 2 years, $412,792
  • Tore Eid, NIH, Temporal Lobe Epilepsy—Validation of a New Animal Model, 2 years, $397,259
  • Alison Galvani, NSF, Collaborative Research: Modeling and Behavioral Evaluation of Social Dynamics in Prevention Decisions, 3 years, $377,485
  • Charles Greer, NIH, Odorants, Receptors and Glomeruli, 1.5 years, $1,289,556
  • Lyndsay Harris, Department of Defense, Molecular Classifications of Response to Therapy in HER2 Positive, Early-Stage Breast Cancer, 2.25 years, $994,847
  • Raimund Herzog, NIH, Adaptations of CNS Metabolism to Hypoglycemia in Diabetes, 2 years, $116,072
  • Hoby Hetherington, NIH, MRS Measurements of GABA in Temporal Lobe Epilepsy, 1.25 years, $320,151
  • Tamas Horvath, NIH, Ghrelin in Hypothalmic Regulation of Energy Balance, 4 years, $1,289,357
  • James Howe, NIH, Single Channel Properties and Structure of Glutamate Receptors, 4 years, $1,446,394
  • Ruslan Medzhitov, NIH, TLRs in Host-Commensal Interactions, 4 years, $1,355,648
  • George Richerson, NIH, Developmental Defects in Serotonin Neurons and the Response to O2 and CO2, 5 years, $1,657,482
  • Joseph Santos-Sacchi, NIH, Structural Correlates of Prestin Activity, 3 years, $1,053,470
  • Dieter Söll, NSF, Expanding the Genetic Code with Phosphoserine, 3 years, $522,375
  • Scott Strobel, NSF, International: Undergraduate Rainforest Expedition and Laboratory, 2 years, $60,000
  • Zhaoxia Sun, Department of Defense, TSC1 and the Cilium in Zebrafish Kidney, 2 years, $221,100
  • Fayyaz Sutterwala, NIH, The Role of NALPs in Innate Immunity, 4 years, $504,280
  • David Willhite, NIH, Transsynaptic Tracing of Olfactory Bulb Input to the Olfactory Cortex, 3 years, $247,895

  • Ali Abu-Alfa, Abbott Laboratories Inc., Educational Grant for Chronic Kidney Disease Center of Excellence, 1 year, $40,250
  • Maysa Abu-Khalaf, Breast Cancer Alliance, Inc., An Integrated Approach to Biomarker Validation in Patients with HER-2 Positive Metastatic Breast Cancer Treated with Rapamycin (Rapamune) to Overcome Resistance to the HER-2 Targeted Therapy Trastuzum, 2 years, $125,000
  • Karen Anderson, Albert Einstein College of Medicine, The Role of Viral and Cellular Proteins in Early Events of HIV-1 Replication, 5 years, $82,500
  • Michael Bloch, American Academy of Child and Adolescent Psychiatry, Clinical and Volumetric MRI Predictors of the Adult Outcome in Pediatric Obsessive-Compulsive Disorder, 1 year, $9,000
  • Hal Blumenfeld, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Impaired Consciousness in Epilepsy: Mechanisms and Consequences, 5 years, $595,791
  • Judson Brewer, The Mind & Life Institute, Mindful Training as Treatment and Mechanistic Probe for Drug Addiction, 1 year, $10,000
  • Stacy Castner, Pfizer Inc., Discovery Proposal for Nonhuman Primate Models Relevant to Schizophrenia, 1 year, $374,617
  • Katarzyna Chawarska, Autism Speaks, Computational Modeling of Visual Attention in Young Children with ASD, 2 years, $54,000
  • Michael Chen, American Society of Maxillofacial Surgeons, National Outcomes Studies in Craniofacial Surgery, 1 year, $6,680
  • Judy Cho, Burroughs Wellcome Fund, Characterization of Expression Patterns in Monocyte-Derived Cells in Inflammatory Bowel Disease, 1 year, $75,000
  • Dylan Clyne, Robert Leet and Clara Guthrie Patterson Trust, Neuronal Control of Courtship in Drosophila, 2 years, $104,000
  • James Comer, Nellie Mae Education Foundation, Nellie Mae Directors Grant, 1 year, $20,000
  • David Cone, The Laerdal Foundation for Acute Medicine, Virtual Reality for Disaster Triage Research, 1 year, $12,260
  • Michael Crair, Rett Syndrome Research Foundation, Examining the Role of MeCP2 in Regulating the Plasticity and Development of Synapses and Circuits in Mouse Somatosensory Barrel Cortex, 3 years, $100,000
  • Daryn David, The International Psychoanalytical Association, Investigating the Internal Working Model Concept, 1 year, $4,000
  • Nancy Dunbar, Endocrine Fellows Foundation, Characterization of Cystic Fibrosis Bone Disease Using Three Mouse Genetic Models, 1 year, $7,500
  • John Forrest, Doris Duke Charitable Foundation, International Clinical Research Fellowships (ICRF) in Africa Pilot Program, 1.5 years, $130,000
  • Gerald Friedland, University of Connecticut, Integrating HIV Prevention into Clinical Care for PLWHA in South Africa, 5 years, $217,999
  • Anna-Rachel Gallagher, PKD Foundation for Research in Polycystic Kidney Disease, Pathogenesis of Congenital Hepatic Fibrosis and Biliary Cyst Formation in ARPRD, 1 year, $75,000
  • Alan Garen, Prostate Cancer Foundation, Targeted Nanoparticles to Deliver the Icon Gene for Prostate Cancer Immunotherapy, 1 year, $100,000
  • Kim Good, Arthritis Foundation of Australia, Role of B7 Family Members in Enhanced Secondary Immune Responses, 1 year, $38,798
  • Carlos Grilo, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, RCT for Obesity and Binge Eating in Monolingual Hispanic Persons, 3 years, $239,997
  • Bryan Hains, Mike Utley Foundation, Rescuing Motor Function after Spinal Cord Injury, 1 year, $47,833
  • Kevan Herold, Juvenile Diabetes Research Foundation Int’l, Islet Growth in NOD Mice Tolerant to Autoimmune Diabetes, 3 years, $495,000; Juvenile Diabetes Research Foundation Int’l, Mechanistic Studies and Identification of Biomarkers in Patients with T1DM, 4 years, $660,000
  • Melinda Irwin, American Cancer Society, Inc., Yale Exercise and Breast Cancer Survivorship Study: An Ancillary Study, 2 years, $202,000
  • Mustafa Khokha, March of Dimes, The BMP Antagonists, Noggin and Gremlin, are Required for Axial Skeleton Formation, 2 years, $150,000
  • Riku Kiviranta, International Bone & Mineral Society, The Roles of Delta FosB and MC-33, A Novel Zinc Finger Containing Protein, in Osteoblast and AdipocyteDifferentiation, 2 years, $40,000
  • Anthony Koleske, American Heart Association, Regulation of Directed Cell Migration by Adhesive Cues, 5 years, $500,000
  • John Leventhal, Salomon Family Foundation, Inc., Bridging Mental Health Services for Sexually Abused Children and Their Families, 2 years, $148,162
  • Becca Levy, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Promoting Positive Age Self-Stereotypes: An Intervention, 5 years, $595,799
  • Ming Li, Arthritis Foundation, TGF-Beta Regulation of T Cell Responses in Collagen Induced Arthritis, 6 months, $75,000
  • Yilun Liu, The Milo Gladstein Foundation, Genome Instability and Tumorigenesis: The Roles of BLM and RecQ5 Helicases, 1 year, $75,000
  • Richard Matthay, Pfizer Inc., State Chest Conference, 6 months, $5,180
  • Qing Miao, American Heart Association, Role of Nogo-B Receptor in Regulating Endothelial Cell Functions, 4 years, $259,992
  • Gil Mor, Wayne State University, Services in Support of the Perinatology Research Branch, 1 year, $134,387
  • Shin Nagayama, Robert Leet and Clara Guthrie Patterson Trust, Individual Neuronal Contributions to the Function of a Cortical Network Module, 2 years, $96,000
  • Angus Nairn, Rockefeller University, Role of CK1 in Alzheimer Disease Etiology, 1 year, $49,171
  • Michael Pantalon, National Alliance for Research on Schizophrenia and Depression, Efficacy of Motivational Enhancement for Bipolar Postpartum Women, 2 years, $60,000
  • Pasko Rakic, Autism Speaks, Effect of Non-Steroidal Anti-Inflammation Drugs on Neuronal Migration, 2 years, $101,000
  • Ann Rasmusson, National Alliance for Research on Schizophrenia and Depression, Neurobiological Predictors of Response to Cognitive Processing Therapy for PTSD in Women with and without Major Depression, 2 years, $59,891
  • Michael Robek, Health Research Inc., Inhibition of Virus Replication by Lambda Interferon, 1 year, $122,868
  • Rachel Roth, PhRMA Foundation, Regulation of Energy Expenditure and Lipid Metabolism by the Mitogen Activated Protein Kinase Phosphatase-1, 2 years, $40,000
  • David Rothstein, Roche Organ Transplantation Foundation, Mechanisms of Treg Generation by Tolerogenic Agents in Transplantation, 3 years, $242,266
  • Nancy Ruddle, National Multiple Sclerosis Society, Characterization of Pathogenic Myelin Oligodendrocyte Antibodies in Multiple Sclerosis, 1 year, $44,000
  • Gary Rudnick, Autism Speaks, The N-Terminus of Serotonin Transporter—A Role in Regulation, 3 years, $82,000
  • Masanori Sasaki, Paralyzed Veterans of America, Cortical Neuronal Protection in Spinal Cord Injury Following Transplantation of BDNF-hMSCs, 2 years, $149,040
  • Srijan Sen, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Investigation into the Interaction between Genes and Stress in the Etiology of Depression in Interns, 2 years, $88,039
  • Nenad Sestan, Autism Speaks, Role of Cell Adhesion Molecule in Cortical Minicolumn, 2 years, $99,000
  • Gerald Shadel, National Organization for Hearing Research Foundation, The Role of Dual-Function Transcription Factor/rRNA Methyltransferase in Modulating Mitochondrial Translation and Susceptibility, 1 year, $20,000
  • Edward Snyder, Richard D. Frisbee III Foundation, Richard D. Frisbee III Visiting Professorship, 2 years, $6,600
  • Zhaoxia Sun, PKD Foundation for Research in Polycystic Kidney Disease, Role of Pontin in Cilia Assembly and Cyst Formation in Zebrafish, 2 years, $150,000
  • Yufeng Zhou, American Heart Association, Determine the Structural Basis of hERG Channel Blockade at Atomic Resolution, 4 months, $65,000